Omegut 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.03 (5 x 10: ৳ 351.51)
Strip Price: ৳ 70.30

Medicine Details

Category Details
Generic Omeprazole
Company Popular pharmaceuticals ltd
Also available as
Omegut 20 mg capsule Omegut 40 mg injection

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

Inhibitor of gastric acid secretion

Dosage

  • 20 mg once daily for 4 weeks in duodenal ulceration
  • 40 mg once daily for severe or recurrent cases
  • 40 mg once daily for 8 weeks in refractory gastro-esophageal reflux disease
  • 10-20 mg daily for long-term management of acid reflux disease
  • 10-20 mg once daily for 2-4 weeks in acid-related dyspepsia
  • 40 mg prophylaxis of acid aspiration before surgery
  • 60 mg once daily for Zollinger-Ellison syndrome
  • 20 mg twice daily with antimicrobial agents for Helicobacter pylori eradication
  • Pediatric use: 10-40 mg once daily based on body weight
  • IV Injection for various indications

Administration

Must be administered as intravenous injection or infusion

Interaction

  • Decreased intragastric acidity affecting absorption of other medications
  • Metabolized in the liver through cytochrome P450
  • Possible delay in elimination of diazepam, phenytoin, and warfarin
  • Monitoring required for patients receiving warfarin or phenytoin
  • Increased plasma concentrations during concomitant clarithromycin administration
  • No evidence of interaction with several medications including antacids

Contraindications

Known hypersensitivity to omeprazole, suspicion of gastric ulcer as malignancy

Side Effects

  • Mild and reversible adverse reactions
  • Skin rash, urticaria and pruritus
  • Photosensitivity, bullous eruption, erythema multiforme
  • Diarrhoea, headache, constipation, nausea/vomiting
  • Dizziness, somnolence, insomnia, vertigo
  • Reversible mental confusion and agitation
  • Arthritic and myalgic symptoms
  • Possible increases in liver enzymes

Pregnancy & Lactation

Can be used during pregnancy, information on passage into breast milk is not available

Precautions & Warnings

  • Avoid concomitant use with clopidogrel
  • Possible association with increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted in long-term treatment
  • Concomitant use with methotrexate may lead to toxicities

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Keep in a dry place away from light and heat, out of the reach of children

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