Omelet 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.02 (60's pack: ৳ 301.20)
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Amulet pharmaceuticals ltd |
| Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of antisecretory effect occurs within one hour
- Maximum effect occurs within two hours
- Inhibition of secretion lasts up to 72 hours
Dosage
- Oral administration
- Benign gastric and duodenal ulcer treatment regimen
- NSAID-associated duodenal or gastric ulcer treatment regimen
- Gastro-esophageal reflux disease treatment regimen
- Long-term management of acid reflux disease dosage
- Acid-related dyspepsia dosage
- Prophylaxis of acid aspiration dosage
- Zollinger-Ellison syndrome regimen
- Helicobacter pylori eradication regimen
- Paediatric use in severe ulcerating reflux esophagitis
- IV Injection directions for prophylaxis of acid aspiration, duodenal ulcer, gastric ulcer, reflux oesophagitis, and Zollinger-Ellison syndrome
Administration
- Direction for use of IV Injection
- Direction for use of IV Infusion
- Must be given as a slow intravenous injection
- Intravenous infusion over a period of 20-30 minutes or more
- Reconstituted solution should not be mixed or co-administered in the same infusion set with any other drug
Interaction
- Interaction with ketoconazole
- Metabolism through cytochrome P450
- Potential interactions with diazepam, phenytoin, warfarin, clarithromycin, amoxicillin, metronidazole, cyclosporin, and more
Contraindications
- Known hypersensitivity
- Exclusion of malignancy in suspected gastric ulcer cases before treatment
Side Effects
- Skin rash
- Urticaria
- Pruritus
- Photosensitivity
- Diarrhoea
- Headache
- Nausea/vomiting
- Flatulence
- Abdominal pain
- Dry mouth
- Stomatitis
- Candidiasis
- Paraesthesia
- Dizziness
- Light headedness
- Somnolence
- Insomnia
- Vertigo
- Mental confusion
- Agitation
- Depression
- Hallucinations
- Arthritic and myalgic symptoms
- Blurred vision
- Taste disturbance
- Peripheral oedema
- Increased sweating
- Agranulocytosis
- Pancytopenia
- Malaise
- Fever
- Bronchospasm
- Encephalopathy
- Hepatitis
- Interstitial nephritis
- Hepatic failure
- Increases in liver enzymes
Pregnancy & Lactation
- No adverse effects of Omeprazole on pregnancy or on the health of the fetus/newborn child
- Use during pregnancy
- Discontinuation of breastfeeding if essential
Precautions & Warnings
- Avoid concomitant use of clopidogrel
- Potential increased risk for osteoporosis-related fractures
- Atrophic gastritis noted occasionally in long-term treatment
- Concomitant use with methotrexate may lead to toxicities
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
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