Omelet 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.02 (60's pack: ৳ 301.20)

Medicine Details

Category Details
Generic Omeprazole
Company Amulet pharmaceuticals ltd
Also available as
Omelet 40 mg capsule

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of antisecretory effect occurs within one hour
  • Maximum effect occurs within two hours
  • Inhibition of secretion lasts up to 72 hours

Dosage

  • Oral administration
  • Benign gastric and duodenal ulcer treatment regimen
  • NSAID-associated duodenal or gastric ulcer treatment regimen
  • Gastro-esophageal reflux disease treatment regimen
  • Long-term management of acid reflux disease dosage
  • Acid-related dyspepsia dosage
  • Prophylaxis of acid aspiration dosage
  • Zollinger-Ellison syndrome regimen
  • Helicobacter pylori eradication regimen
  • Paediatric use in severe ulcerating reflux esophagitis
  • IV Injection directions for prophylaxis of acid aspiration, duodenal ulcer, gastric ulcer, reflux oesophagitis, and Zollinger-Ellison syndrome

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • Must be given as a slow intravenous injection
  • Intravenous infusion over a period of 20-30 minutes or more
  • Reconstituted solution should not be mixed or co-administered in the same infusion set with any other drug

Interaction

  • Interaction with ketoconazole
  • Metabolism through cytochrome P450
  • Potential interactions with diazepam, phenytoin, warfarin, clarithromycin, amoxicillin, metronidazole, cyclosporin, and more

Contraindications

  • Known hypersensitivity
  • Exclusion of malignancy in suspected gastric ulcer cases before treatment

Side Effects

  • Skin rash
  • Urticaria
  • Pruritus
  • Photosensitivity
  • Diarrhoea
  • Headache
  • Nausea/vomiting
  • Flatulence
  • Abdominal pain
  • Dry mouth
  • Stomatitis
  • Candidiasis
  • Paraesthesia
  • Dizziness
  • Light headedness
  • Somnolence
  • Insomnia
  • Vertigo
  • Mental confusion
  • Agitation
  • Depression
  • Hallucinations
  • Arthritic and myalgic symptoms
  • Blurred vision
  • Taste disturbance
  • Peripheral oedema
  • Increased sweating
  • Agranulocytosis
  • Pancytopenia
  • Malaise
  • Fever
  • Bronchospasm
  • Encephalopathy
  • Hepatitis
  • Interstitial nephritis
  • Hepatic failure
  • Increases in liver enzymes

Pregnancy & Lactation

  • No adverse effects of Omeprazole on pregnancy or on the health of the fetus/newborn child
  • Use during pregnancy
  • Discontinuation of breastfeeding if essential

Precautions & Warnings

  • Avoid concomitant use of clopidogrel
  • Potential increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted occasionally in long-term treatment
  • Concomitant use with methotrexate may lead to toxicities

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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