Omenta 40 mg/vial (IV Injection)
40 mg vial: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Jenphar bangladesh ltd |
| Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of the antisecretory effect within one hour
- Maximum effect occurring within two hours
- Inhibition of secretion lasts up to 72 hours
Dosage
- 20 mg once daily for benign gastric and duodenal ulcer for 4 weeks in duodenal ulceration, 8 weeks in gastric ulceration
- 40 mg daily in severe or recurrent cases of gastric and duodenal ulcer
- 10-20 mg daily for acid-related dyspepsia for 2-4 weeks
Administration
- Omeprazole IV injection should be given as a slow intravenous injection
- Omeprazole IV infusion should be given as an intravenous infusion over a period of 20-30 minutes or more
Interaction
- Decreased intragastric acidity may reduce the absorption of ketoconazole during Omenta treatment
- Concomitant treatment with Omenta and digoxin lead to a 10% increase in the bioavailability of digoxin
Contraindications
- Known hypersensitivity to Omeprazole
- Suspicion of gastric ulcer without excluding the possibility of malignancy
Side Effects
- Skin rash, urticaria, and pruritus
- Diarrhea and headache
- Constipation, nausea/vomiting, flatulence, and abdominal pain
- Dry mouth, stomatitis, and candidiasis
Pregnancy & Lactation
- Omeprazole can be used during pregnancy
- Breast feeding should be discontinued if the use of Omeprazole is considered essential
Precautions & Warnings
- Avoid concomitant use of clopidogrel and Omenta
- Increased risk for osteoporosis-related fractures with PPI therapy
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat