Omep 10 mg (Capsule (Enteric Coated))
Unit Price: ৳ 2.00 (6 x 10: ৳ 120.00)
Strip Price: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Treatment of gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of the antisecretory effect within one hour
- Maximum effect occurring within two hours
- Inhibition of secretion lasts up to 72 hours
- Secretory activity returns gradually over 3 to 5 days
Dosage
- Oral dosage for different conditions
- IV injection dosage for various conditions
- Pediatric use in severe ulcerating reflux esophagitis
Administration
- Direction for use of IV Injection
- Direction for use of IV Infusion
- Preparation of IV injection solution
- Preparation of IV infusion solution
Interaction
- Decreased intragastric acidity affecting the absorption of ketoconazole
- Metabolism in the liver through cytochrome P450 affecting the elimination of certain medications
- Plasma concentrations of Omep and clarithromycin are increased during concomitant administration
Contraindications
- Contraindicated in patients with known hypersensitivity to it
- Possibility of malignancy should be excluded before treatment
Side Effects
- Mild and reversible adverse reactions
- Skin rash, urticaria, and pruritus
- Photosensitivity, bullous eruption, and erythema multiforme
- Diarrhea and headache
- Gastrointestinal reactions like constipation, nausea/vomiting, flatulence, and abdominal pain
Pregnancy & Lactation
- No adverse effects of Omeprazole on pregnancy or on the health of the fetus/newborn child
- No information available on the passage of Omeprazole into breast milk or its effects on the neonate
- Breastfeeding should be discontinued if the use of Omeprazole is considered essential
Precautions & Warnings
- Avoid concomitant use of clopidogrel and Omep
- Increased risk for osteoporosis-related fractures
- Atrophic gastritis noted occasionally in gastric corpus biopsies from long-term treatment
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children