Omep 10 mg (Capsule (Enteric Coated))

Unit Price: ৳ 2.00 (6 x 10: ৳ 120.00)
Strip Price: ৳ 20.00

Medicine Details

Category Details
Generic Omeprazole
Company Aristopharma ltd
Also available as
Omep 20 mg capsule Omep 40 mg capsule Omep 40 mg injection

Indications

  • Treatment of gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of the antisecretory effect within one hour
  • Maximum effect occurring within two hours
  • Inhibition of secretion lasts up to 72 hours
  • Secretory activity returns gradually over 3 to 5 days

Dosage

  • Oral dosage for different conditions
  • IV injection dosage for various conditions
  • Pediatric use in severe ulcerating reflux esophagitis

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • Preparation of IV injection solution
  • Preparation of IV infusion solution

Interaction

  • Decreased intragastric acidity affecting the absorption of ketoconazole
  • Metabolism in the liver through cytochrome P450 affecting the elimination of certain medications
  • Plasma concentrations of Omep and clarithromycin are increased during concomitant administration

Contraindications

  • Contraindicated in patients with known hypersensitivity to it
  • Possibility of malignancy should be excluded before treatment

Side Effects

  • Mild and reversible adverse reactions
  • Skin rash, urticaria, and pruritus
  • Photosensitivity, bullous eruption, and erythema multiforme
  • Diarrhea and headache
  • Gastrointestinal reactions like constipation, nausea/vomiting, flatulence, and abdominal pain

Pregnancy & Lactation

  • No adverse effects of Omeprazole on pregnancy or on the health of the fetus/newborn child
  • No information available on the passage of Omeprazole into breast milk or its effects on the neonate
  • Breastfeeding should be discontinued if the use of Omeprazole is considered essential

Precautions & Warnings

  • Avoid concomitant use of clopidogrel and Omep
  • Increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted occasionally in gastric corpus biopsies from long-term treatment

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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