Omep 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.00 (4 x 7: ৳ 224.00)

Strip Price: ৳ 56.00

Medicine Details

Category	Details
Generic	Omeprazole
Company	Aristopharma ltd
Also available as	Omep 10 mg capsule Omep 20 mg capsule Omep 40 mg injection

Indications

Treatment of gastric and duodenal ulcer
NSAID-associated duodenal and gastric ulcer
Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
Gastro-esophageal reflux disease
Long-term management of acid reflux disease
Acid-related dyspepsia
Severe ulcerating reflux esophagitis
Prophylaxis of acid aspiration during general anesthesia
Zollinger-Ellison syndrome
Helicobacter pylori-induced peptic ulcer

Pharmacology

Omeprazole is an inhibitor of gastric acid secretion. It inhibits gastric acid secretion by blocking hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system in the gastric parietal cell. The onset of the antisecretory effect occurs within one hour, with the maximum effect occurring within two hours and inhibition of secretion lasts up to 72 hours

Dosage

Oral dosage for different conditions
IV Injection dosage for different conditions

Administration

Direction for IV Injection
Direction for IV Infusion

Interaction

Interactions with other medications such as ketoconazole, diazepam, phenytoin, warfarin, clarithromycin, and others

Contraindications

Contraindicated in patients with known hypersensitivity to omeprazole, and when gastric ulcer is suspected with a possibility of malignancy

Side Effects

Skin rash, urticaria, pruritus
Photosensitivity, bullous eruption, erythema multiforme, angioedema, alopecia
Diarrhea, headache, constipation, nausea/vomiting, flatulence, abdominal pain
Dry mouth, stomatitis, candidiasis
Paraesthesia, dizziness, light headedness, feeling faint
Somnolence, insomnia, vertigo
Reversible mental confusion, agitation, depression, hallucinations
Arthritic and myalgic symptoms
Blurred vision, taste disturbance, peripheral edema, increased sweating, gynaecomastia
Leucopenia, thrombocytopenia, agranulocytosis, pancytopenia, anaphylactic shock
Malaise, fever, bronchospasm, encephalopathy, hepatitis, interstitial nephritis, hepatic failure
Increases in liver enzymes

Pregnancy & Lactation

Results from three prospective epidemiological studies indicate no adverse effects of Omeprazole on pregnancy or on the health of the fetus/newborn child. Omeprazole can be used during pregnancy. No information available on the passage of Omeprazole into breast milk or its effects on the neonate. Breast-feeding should be discontinued if the use of Omeprazole is essential. Not established for pediatric patients less than 18 years of age

Precautions & Warnings

Avoid concomitant use of clopidogrel and Omep
Potential association of PPI therapy with increased risk for osteoporosis-related fractures
Atrophic gastritis noted occasionally in gastric corpus biopsies from patients treated long-term with Omep
Concomitant use of PPIs with methotrexate may lead to methotrexate toxicities