Omep 40 mg/vial (IV Injection)

40 mg vial: ৳ 80.00

Medicine Details

Category	Details
Generic	Omeprazole
Company	Aristopharma ltd
Also available as	Omep 10 mg capsule Omep 20 mg capsule Omep 40 mg capsule

Gastric and duodenal ulcer
NSAID-associated duodenal and gastric ulcer
Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
Gastro-esophageal reflux disease
Long-term management of acid reflux disease
Acid-related dyspepsia
Severe ulcerating reflux esophagitis
Prophylaxis of acid aspiration during general anesthesia
Zollinger-Ellison syndrome
Helicobacter pylori-induced peptic ulcer

20 mg once daily for benign gastric and duodenal ulcer
40 mg daily for severe or recurrent cases
10-20 mg daily for duodenal ulcer prevention
20 mg once daily for NSAID-associated duodenal or gastric ulcer for 4 weeks
20 mg once daily for 4 weeks for GERD
40 mg once daily for refractory GERD for 8 weeks
10-20 mg daily for long-term management of acid reflux disease
10-20 mg once daily for acid-related dyspepsia
40 mg prophylaxis of acid aspiration before surgery
60 mg once daily for Zollinger-Ellison syndrome
20 mg twice daily with antimicrobial agents for H.pylori eradication regimen
10-40 mg once daily for severe ulcerating reflux esophagitis
40 mg slowly as IV injection for prophylaxis of acid aspiration
40 mg Omeprazole IV once daily for duodenal ulcer, gastric ulcer or reflux esophagitis where oral medication is inappropriate
Initial 60 mg daily dose for Zollinger-Ellison syndrome given intravenously
Omeprazole IV infusion over 20-30 minutes or more
Pediatric use: 10-40 mg once daily based on body-weight

IV Injection for intravenous administration only
IV infusion over 20-30 minutes or more
Reconstitution required with specific volumes of saline or dextrose for infusion
Solution for IV injection should be used within 4 hours of reconstitution
Solution for IV infusion should be used within 12 hours when dissolved in saline and within 6 hours when dissolved in 5% Dextrose

Reduction in absorption of ketoconazole during treatment
Metabolism via cytochrome P450 leading to delay in elimination of diazepam, phenytoin, and warfarin
Plasma concentration increase during concomitant administration with clarithromycin
No evidence of interaction with various drugs such as phenacetin, theophylline, caffeine, propranolol, etc.
Increased bioavailability of digoxin due to increased intragastric pH during simultaneous treatment with Omeprazole
No effect on absorption by alcohol or food
Useful interactions during H.pylori eradication and continuation of certain treatments

Known hypersensitivity to Omeprazole
Need to exclude possibility of malignancy before treatment if gastric ulcer is suspected

Mild and reversible adverse reactions
Skin rash, urticaria, and pruritus
Photosensitivity, bullous eruption, erythema multiforme, angioedema, and alopecia reported in isolated cases
Diarrhea, headache, constipation, nausea/vomiting, and abdominal pain
Dry mouth, stomatitis, and candidiasis reported in isolated cases
Paraesthesia, dizziness, and light-headedness
Mental confusion, agitation, depression, and hallucinations predominantly in severely ill patients
Arthritic and myalgic symptoms, blurred vision, taste disturbance, gynaecomastia, and changes in liver enzymes observed in isolated cases

No adverse effects reported on pregnancy or the health of the fetus/newborn child
Use during pregnancy indicated
No information available on passage into breast milk or effects on the neonate
Breastfeeding discontinuation recommended if essential use of Omeprazole
Safety and effectiveness not established in pediatric patients less than 18 years of age