Amupime 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 300.00

Medicine Details

Indications

  • Treatment of moderate to severe pneumonia
  • Treatment of febrile neutropenia
  • Treatment of uncomplicated and complicated urinary tract infections
  • Treatment of uncomplicated skin and skin structure infections
  • Treatment of complicated intra-abdominal infections

Pharmacology

  • Bactericidal action
  • Disruption of peptidoglycan synthesis
  • Mode of action similar to penicillins

Dosage & Administration

  • Intravenous administration
  • Dosage for different infections
  • Duration of treatment for different infections
  • Special considerations for febrile neutropenic patients

Interaction

  • Potential interaction with aminoglycosides
  • Nephrotoxicity risk with concomitant administration of potent diuretics

Contraindications

  • Immediate hypersensitivity reactions to cefepime
  • Contraindicated in patients allergic to cephalosporins, penicillin, or other betalactum antibiotics

Side Effects

  • Potential adverse reactions
  • Immediate hypersensitivity reactions

Pregnancy & Lactation

  • Pregnancy category B
  • Excretion in human breast milk
  • Caution in administration to nursing women

Precautions & Warnings

  • Avoid use in absence of bacterial infection
  • Risk of overgrowth of non-susceptible microorganisms
  • Association with fall in prothrombin activity
  • Prescribe with caution in individuals with gastrointestinal disease
  • Effect of arginine on glucose metabolism and serum potassium levels

Use in Special Populations

  • Pediatric use
  • Geriatric use
  • Impaired hepatic function
  • Impaired renal function

Overdose Effects

  • Observation and supportive treatment for overdose
  • Hemodialysis recommended in renal insufficiency

Therapeutic Class

  • Fourth generation Cephalosporins

Reconstitution

  • Intravenous reconstitution
  • Compatibility with different IV infusion fluids
  • Intramuscular reconstitution
  • Reconstitution details for different vial sizes

Storage Conditions

  • Expiry date
  • Keep out of reach of children
  • Dispensing only on prescription of a registered physician

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