Xtrapime 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 300.00

Medicine Details

Category Details
Generic Cefepime hydrochloride
Company Asiatic laboratories ltd
Also available as
Xtrapime 1 gm injection Xtrapime 2 gm injection

Title

  • Xtrapime (Cefepime) - 4th Generation Cephalosporin Antibiotic

Categories

  • Antibiotics
  • Intravenous Medications
  • Infectious Disease Treatment

Description

  • Broad-spectrum antibiotic for treatment of various infections
  • Bactericidal effect against susceptible strains of microorganisms
  • Disrupts synthesis of peptidoglycan layer in bacterial cell walls
  • Administration intravenously over approximately 30 minutes

Dimensions

  • N/A

Color options

  • N/A

Functions

  • Treatment of moderate to severe pneumonia caused by specific microorganisms
  • Empiric therapy for febrile neutropenic patients
  • Treatment of uncomplicated and complicated urinary tract infections
  • Treatment of uncomplicated skin and skin structure infections
  • Treatment of complicated intra-abdominal infections

Materials

  • Active ingredient: Cefepime

Technical specifications

  • Dosage forms: Intravenous and Intramuscular
  • Reconstitution with specified diluents for administration
  • Range of recommended dosages for different indications

Design elements

  • N/A

Usability features

  • Pregnancy Category B
  • Excreted in human breast milk in very low concentrations
  • Caution advised when administered to nursing women
  • Dose adjustment required for patients with impaired renal function
  • Careful monitoring of renal function in geriatric patients
  • Adverse events in geriatric patients with renal insufficiency

Interaction

  • Monitoring of renal function if high doses of aminoglycosides are administered
  • Potential nephrotoxicity and ototoxicity of aminoglycoside antibiotics
  • Nephrotoxicity reported with concomitant administration of cephalosporins and diuretics

Contraindications

  • Immediate hypersensitivity reactions to cefepime or cephalosporin class of antibiotics

Side effects

  • Potential for immediate hypersensitivity reactions

Pregnancy and lactation

  • Category B drug during pregnancy
  • Caution required in nursing women due to excretion in breast milk

Precautions and warnings

  • Avoid prescribing in absence of proven or strongly suspected bacterial infection
  • Prolonged use may result in overgrowth of non-susceptible microorganisms
  • Association with a fall in prothrombin activity
  • Use with caution in patients with gastrointestinal disease
  • Potential alteration of glucose metabolism and serum potassium levels with arginine

Special populations

  • Pediatric use: Maximum dose should not exceed recommended adult dose
  • Geriatric use: Risk of serious adverse events in patients with renal insufficiency
  • No adjustment necessary for patients with impaired hepatic function
  • Dose adjustment required for patients with impaired renal function

Overdose effects

  • Careful observation and supportive treatment for patients who receive an overdose
  • Recommendation of hemodialysis in the presence of renal insufficiency
  • Symptoms include encephalopathy, myoclonus, seizures, and neuromuscular excitability

Storage conditions

  • Not for use after expiry date
  • Keep out of reach of children
  • Dispense only on prescription of a registered physician

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