Axepime 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 550.00

Medicine Details

Category Details
Generic Cefepime hydrochloride
Company Euro pharma ltd

Title

  • Axepime

Categories

  • Antibiotics
  • Cephalosporins
  • Medication
  • Pharmaceuticals

Indications

  • Treatment of moderate to severe pneumonia caused by specific microorganisms
  • Empiric treatment for febrile neutropenic patients
  • Treatment of uncomplicated and complicated urinary tract infections
  • Treatment of uncomplicated skin and skin structure infections
  • Treatment of complicated intra-abdominal infections

Pharmacology

  • Bactericidal action
  • Disruption of peptidoglycan synthesis in bacterial cell walls
  • Mode of action similar to penicillins

Dosage & Administration

  • Intravenous administration over approximately 30 minutes
  • Specific dosage regimens for various infections

Interaction

  • Monitoring required for concomitant administration with high doses of aminoglycosides
  • Nephrotoxicity potential with potent diuretics

Contraindications

  • Immediate hypersensitivity reactions to cefepime or cephalosporin class of antibiotics
  • Allergy to penicillin or other beta-lactam antibiotics

Side Effects

  • Immediate hypersensitivity reactions

Pregnancy & Lactation

  • Pregnancy Category B
  • Excretion in low concentrations in human breast milk

Precautions & Warnings

  • Avoid use in absence of proven or strongly suspected bacterial infection
  • Risk of overgrowth of non-susceptible microorganisms
  • Potential impact on prothrombin activity
  • Caution in individuals with history of gastrointestinal disease
  • Potential alteration of glucose metabolism and serum potassium

Use in Special Populations

  • Pediatric use
  • Geriatric use and associated adverse events
  • No dose adjustment necessary for impaired hepatic function
  • Dose adjustment required for impaired renal function

Overdose Effects

  • Supportive treatment for patients who receive an overdose
  • Recommendation for hemodialysis in the presence of renal insufficiency
  • Symptoms of overdose

Therapeutic Class

  • Fourth generation cephalosporins

Reconstitution

  • Instructions for intravenous and intramuscular administration
  • Compatibility with various diluents and IV infusion fluids
  • Specific volume information for IV and IM administration for various vial sizes

Storage Conditions

  • Do not use beyond expiry date
  • Keep out of reach of children
  • Dispense only on prescription of a registered physician

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