Ximepime 2 gm/vial (IV Injection)
2 gm vial: ৳ 1,100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefepime hydrochloride |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of moderate to severe pneumonia
- Empiric treatment of febrile neutropenic patients
- Treatment of urinary tract infections
- Treatment of skin and skin structure infections
- Treatment of complicated intra-abdominal infections
Pharmacology
- Bactericidal action
- Disruption of peptidoglycan synthesis
- Mode of action similar to penicillins
- Importance for cell wall structural integrity
Dosage & Administration
- Intravenous administration
- Administration over 30 minutes
- Specific doses for different infections
Interaction
- Monitor renal function when administering with aminoglycosides
- Potential nephrotoxicity and ototoxicity
Contraindications
- Immediate hypersensitivity reactions
Side Effects
- Immediate hypersensitivity reactions
- Increase risk of drug-resistant bacteria
Pregnancy & Lactation
- Pregnancy Category B
- Excretion in breast milk
- Caution when administered to nursing women
Precautions & Warnings
- Prescribing without proven or suspected bacterial infection
- Prolonged use may result in overgrowth of non-susceptible microorganisms
- Association with fall in prothrombin activity
- Prescribed with caution in individuals with gastrointestinal disease
Use in Special Populations
- Pediatric use
- Geriatric use
- Impaired hepatic function
- Impaired renal function
Overdose Effects
- Careful observation
- Supportive treatment
- Hemodialysis for renal insufficiency
Therapeutic Class
- Fourth generation Cephalosporins
Reconstitution
- Intravenous and Intramuscular administration
- Compatibility with various IV infusion fluids
- Specific diluent amounts for different vial sizes
Storage Conditions
- Expiry date
- Keep out of reach of children
- Dispensed only on prescription