Ximepime 2 gm/vial (IV Injection)

2 gm vial: ৳ 1,100.00

Medicine Details

Category	Details
Generic	Cefepime hydrochloride
Company	Globe pharmaceuticals ltd
Also available as	Ximepime 500 mg injection Ximepime 1 gm injection

Indications

Treatment of moderate to severe pneumonia
Empiric treatment of febrile neutropenic patients
Treatment of urinary tract infections
Treatment of skin and skin structure infections
Treatment of complicated intra-abdominal infections

Pharmacology

Bactericidal action
Disruption of peptidoglycan synthesis
Mode of action similar to penicillins
Importance for cell wall structural integrity

Dosage & Administration

Intravenous administration
Administration over 30 minutes
Specific doses for different infections

Interaction

Monitor renal function when administering with aminoglycosides
Potential nephrotoxicity and ototoxicity

Contraindications

Immediate hypersensitivity reactions

Side Effects

Immediate hypersensitivity reactions
Increase risk of drug-resistant bacteria

Pregnancy & Lactation

Pregnancy Category B
Excretion in breast milk
Caution when administered to nursing women

Precautions & Warnings

Prescribing without proven or suspected bacterial infection
Prolonged use may result in overgrowth of non-susceptible microorganisms
Association with fall in prothrombin activity
Prescribed with caution in individuals with gastrointestinal disease

Use in Special Populations

Pediatric use
Geriatric use
Impaired hepatic function
Impaired renal function

Overdose Effects

Careful observation
Supportive treatment
Hemodialysis for renal insufficiency

Therapeutic Class

Fourth generation Cephalosporins

Reconstitution

Intravenous and Intramuscular administration
Compatibility with various IV infusion fluids
Specific diluent amounts for different vial sizes

Storage Conditions

Expiry date
Keep out of reach of children
Dispensed only on prescription

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