Omesil 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.75 (10 x 10: ৳ 575.00)
Strip Price: ৳ 57.50
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Silva pharmaceuticals ltd |
Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Acid reflux disease long-term management
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of antisecretory effect within one hour
- Maximum effect within two hours
- Inhibition of secretion lasts up to 72 hours
- Gradual return of secretory activity over 3 to 5 days after discontinuation
Dosage
- Different dosages for various conditions like ulcers, reflux diseases, dyspepsia
- Oral and IV injection dosing instructions
- Maintenance doses for recurrent ulcers
- Dosages for pediatric use in reflux esophagitis
Administration
- Direction for IV injection use
- Direction for IV infusion use
- Reconstitution instructions
- Usage timeline after reconstitution
- Instructions for preparation and administration
Interaction
- Interactions with ketoconazole, diazepam, phenytoin, warfarin
- Monitoring of patients receiving warfarin or phenytoin
- Induction of cytochrome P450 by Omesil
Contraindications
- Known hypersensitivity to omeprazole
- Exclusion of malignancy possibility before treatment initiation
Side Effects
- Mild and reversible adverse reactions
- Skin rash, urticaria, pruritus
- Photosensitivity, bullous eruption, erythema multiforme
- Gastrointestinal reactions like diarrhea, headache, constipation
- Neurological reactions like dizziness, vertigo, somnolence
- Hematological reactions like leucopenia, thrombocytopenia, anemia
Pregnancy & Lactation
- No adverse effects on pregnancy or fetus/newborn child reported
- Safe to use during pregnancy
- No information on passage into breast milk
Precautions & Warnings
- Avoid concomitant use with clopidogrel
- Possible association with increased risk for osteoporosis-related fractures
- Atrophic gastritis in long-term users
- Potential methotrexate toxicities with concomitant use
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children
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