Globexim 200 mg/5 ml (Powder for Suspension)

Indications

• Treatment of upper respiratory tract infections (URTI)
• Treatment of lower respiratory tract infections
• Treatment of urinary tract infections (UTI)
• Bactericidal activity against Gram-positive and Gram-negative organisms
• Clinical efficacy against commonly occurring pathogens

Pharmacology

• Orally active cephalosporin antibiotic
• Third generation semisynthetic cephalosporin antibiotic
• Bactericidal against a broad spectrum of bacteria
• Interferes in the synthesis of bacterial cell wall
• Highly stable in the presence of Beta-lactamase enzyme

Dosage & Administration

• Usual course of treatment is 7 days
• Adult dosage: 200-400 mg daily
• Children dosage based on age and weight
• Absorption not significantly modified by food
• Dosing adjustments in severe renal impairment

Interaction

• Increases in prothrombin times noted in some patients
• Caution required in patients receiving anticoagulant therapy

Contraindications

• Hypersensitivity to cephalosporin antibiotics

Side Effects

• Diarrhea and stool changes
• Gastrointestinal disturbances
• Headache and dizziness
• Allergies in the form of rash, pruritis
• Thrombocytopenia, leukopenia, eosinophilia
• Mild transient change in liver and renal function tests

Pregnancy & Lactation

• Caution advised during pregnancy
• Not known to be excreted in human milk
• Use in lactating women should be exercised with caution

Precautions & Warnings

• Caution in patients with hypersensitivity to other drugs
• Caution in penicillin-sensitive patients
• Severe reactions observed in some patients
• Caution in patients with markedly impaired renal function
• Use in pregnancy and lactation should be carefully considered

Overdose Effects

• Gastric Lavage may be indicated
• No specific antidote exists
• Not removed significantly by hemodialysis or peritoneal dialysis

Therapeutic Class

• Belongs to third generation Cephalosporins

Storage Conditions

• Keep below 30°C temperature
• Protected from light & moisture
• Keep out of the reach of children

Chemical Structure

• Molecular Formula: C16H15N5O7S2
• Chemical Structure Image: [Link to the chemical structure image]

Common Questions about Globexim 200 mg/5 ml Suspension

• What is Globexim 200 mg/5 ml Syrup?
• What are the uses of Globexim 200 mg/5 ml Syrup?
• What are the Side Effects of Globexim 200 mg/5 ml Syrup?
• Instructions for storage and disposal
• Efficacy for treating cold and flu
• Dietary instructions
• Use for treating diarrhoea
• Safety for infants
• Relation to penicillin variants
• Effects on contraception
• Interaction with acetaminophen
• Duration to start working
• Action if no improvement
• Quick tips for usage

Related Brands

• Globexim 200 mg (Capsule) - globex-pharmaceuticals-ltd
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• Cefiget 400 mg (Capsule) - get-well-limited
• Cefiget 200 mg (Capsule) - get-well-limited