Polyxim 200 mg (Capsule)

Unit Price: ৳ 35.00 (12's pack: ৳ 420.00)

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Leon pharmaceuticals ltd
Also available as
Polyxim 400 mg capsule Polyxim 100 mg suspension Polyxim ds 200 mg suspension

Indications

  • Treatment for Upper Respiratory Tract Infections (URTI)
  • Treatment for Lower Respiratory Tract Infections
  • Treatment for Urinary Tract Infections
  • High stability in the presence of beta-lactamase enzymes

Pharmacology

  • Third generation semisynthetic cephalosporin antibiotic
  • Bactericidal against a broad spectrum of gram positive and gram negative bacteria
  • Interferes with the synthesis of bacterial cell wall
  • Highly stable in the presence of Beta-lactamase enzyme
  • Approximately 40%-50% absorption rate

Dosage & Administration

  • Usual course of treatment is 7 days, may be continued for up to 14 days if required
  • Recommended adult dosage is 200-400 mg daily, single dose or two divided doses
  • Recommended dosage for children is 8 mg/kg/day, administered as a single dose or in two divided doses
  • Dosage in Renal Impairment: Dose adjustment in severe renal impairment

Interaction

  • Increases in prothrombin times have been noted in a few patients
  • Care should be taken in patients receiving anticoagulant therapy

Contraindications

  • Not to be used in patients with known hypersensitivity to cephalosporin antibiotics

Side Effects

  • Mild and self-limiting adverse reactions observed
  • Commonly associated with gastrointestinal disturbances such as diarrhea and stool changes
  • Other side effects include nausea, abdominal pain, dizziness, hypersensitivity reactions, hematological and clinical chemistry reactions, and miscellaneous reactions

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • Given with caution to patients who have shown hypersensitivity to other drugs
  • Cautious use for penicillin-sensitive patients
  • Administration with caution in patients with markedly impaired renal function
  • Use in pregnancy and lactation should be avoided unless essential by the physician

Overdose Effects

  • Gastric Lavage may be indicated
  • Polyxim is not removed in significant quantities by hemodialysis or peritoneal dialysis
  • Adverse reactions at high doses did not differ significantly from the profile seen in patients at recommended doses

Therapeutic Class

  • Belongs to the 'Third generation Cephalosporins' therapeutic class

Storage Conditions

  • Keep below 30°C temperature, protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure Image: URL

Common Questions about Polyxim 200 mg Capsule

  • Information about the uses, side effects, storage and disposal instructions, administration to infants, interaction with contraception, interaction with acetaminophen, duration to work, steps if not feeling better, and quick tips

Special Dietary Instruction

  • Continue normal diet unless directed otherwise by a doctor

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