Polyxim 400 mg (Capsule)

Unit Price: ৳ 50.00 (8's pack: ৳ 400.00)

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Leon pharmaceuticals ltd
Also available as
Polyxim 200 mg capsule Polyxim 100 mg suspension Polyxim ds 200 mg suspension

Indications

  • Treatment of Upper Respiratory Tract Infections (URTI)
  • Treatment of Lower Respiratory Tract Infections
  • Treatment of Urinary Tract Infections
  • Bactericidal activity against Gram-positive and Gram-negative organisms

Pharmacology

  • Third generation semisynthetic cephalosporin antibiotic
  • Bactericidal against a broad spectrum of bacteria
  • Interferes in the synthesis of bacterial cell wall
  • Highly stable in the presence of Beta-lactamase enzyme
  • 40%-50% absorption rate with or without food

Dosage & Administration

  • Usual course of treatment: 7 days (up to 14 days if required)
  • Adult dosage: 200-400 mg daily (single dose or in two divided doses)
  • Recommended dosage for children based on age and weight
  • Dosage adjustments in elderly and patients with renal impairment

Interaction

  • Increased prothrombin times in some patients
  • Caution in patients receiving anticoagulant therapy

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Well-tolerated with mild and self-limiting adverse reactions
  • Common side effects: diarrhea, nausea, abdominal pain, dizziness, rash, pruritus
  • Infrequent and reversible hematological and clinical chemistry reactions

Pregnancy & Lactation

  • Limited information on use during pregnancy
  • Caution advised during lactation due to unknown excretion in human milk

Precautions & Warnings

  • Caution in patients with hypersensitivity to other drugs and penicillin-sensitive patients
  • Use with caution in patients with markedly impaired renal function
  • Alters normal flora of the colon leading to antibiotic-associated diarrhea

Overdose Effects

  • Gastric Lavage may be indicated
  • No specific antidote available
  • Not removed significantly by hemodialysis or peritoneal dialysis

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store below 30°C temperature
  • Keep protected from light and moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure: Image

Common Questions

  • What is Polyxim 400 mg Capsule?
  • Uses of Polyxim 400 mg Capsule
  • Side Effects of Polyxim 400 mg Capsule
  • Instructions for storage and disposal
  • Efficacy for treating cold and flu
  • Special dietary instructions
  • Use in infants
  • Comparison with penicillin variant
  • Effect on diarrhea and constipation
  • Interaction with contraception and acetaminophen
  • Onset of action and duration of treatment
  • Request for medical advice and quick tips

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