Polyxim DS 200 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 320.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Leon pharmaceuticals ltd
Also available as
Polyxim 200 mg capsule Polyxim 400 mg capsule Polyxim 100 mg suspension

Title, Categories and Description

  • Polyxim DS 200 mg/5 ml Suspension
  • Orally active cephalosporin antibiotic
  • Treatment of upper respiratory tract infections (URTI)
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Third generation cephalosporins
  • Bactericidal against gram positive and gram negative bacteria
  • Interferes with synthesis of bacterial cell wall
  • Highly stable in the presence of beta-lactamase enzyme
  • Antibiotic for bacterial infections
  • Not suitable for viral infections
  • Storage below 30°C temperature, protected from light & moisture
  • Chemical structure: C16H15N5O7S2

Functionality

  • Bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms
  • Kills bacteria by interfering in the synthesis of bacterial cell wall
  • Treatment for specific acute infections caused by susceptible microorganisms
  • Preventive measure from forming the bacterial protective covering
  • Works by preventing the formation of bacterial cell wall
  • Absorption is about 40% to 50%
  • Absorption not significantly modified by the presence of food
  • Gastric Lavage may be indicated in case of overdose

Dosage & Administration

  • Usual course of treatment is 7 days, may be continued for up to 14 days if required
  • Recommended adult dosage is 200-400 mg daily according to the severity of the infection
  • Recommended dosage for children is 8 mg/kg/day administered as a single dose or in two divided doses
  • Dosage should be adjusted in severe renal impairment
  • Usual dosage for children 5-10 years: 10 ml daily

Side Effects

  • Mild and self-limiting adverse reactions observed in clinical trials
  • Most frequent side-effects are diarrhea and stool changes
  • Gastrointestinal side-effects include nausea, abdominal pain, and vomiting
  • Hematological and clinical chemistry reactions include thrombocytopenia and leukopenia
  • Central nervous system reactions may include headache and dizziness
  • Hypersensitivity reactions may include rash, pruritis, and urticaria

Interaction & Contraindications

  • Increases in prothrombin times have been noted in a few patients
  • Care should be taken in patients receiving anticoagulant therapy
  • Contraindicated in patients with known hypersensitivity to cephalosporin antibiotics

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Drug should be used during pregnancy only if clearly needed
  • Caution should be exercised when administered to a nursing woman

Precautions & Overdose Effects

  • Polyxim DS should be given with caution to patients who have shown hypersensitivity to other drugs
  • Treatment with broad spectrum antibiotics alters the normal flora of the colon
  • Overdose symptoms may require gastric lavage
  • No specific antidote exists

Therapeutic Class & Compound Summary

  • Belongs to third generation cephalosporins
  • Molecular Formula: C16H15N5O7S2

Storage Conditions

  • Keep below 30°C temperature, protected from light & moisture
  • Keep out of the reach of children
  • Proper disposal of expired and unused medications is important

Commonly Asked Questions

  • Common Questions about Polyxim DS 200 mg/5 ml Suspension
  • What is Polyxim DS 200 mg/5 ml Syrup?
  • What are the uses of Polyxim DS 200 mg/5 ml Syrup?
  • What are the Side Effects of Polyxim DS 200 mg/5 ml Syrup?
  • What are the instructions for storage and disposal of Polyxim DS 200 mg/5 ml Syrup?

Related Brands