Xylocef 200 mg (Capsule)

Indications

• Treatment of upper respiratory tract infections (URTI)
• Treatment of lower respiratory tract infections
• Treatment of urinary tract infections (UTI)

Pharmacology

• Bactericidal against a broad spectrum of gram-positive and gram-negative bacteria
• Interferes in the synthesis of bacterial cell wall
• Highly stable in the presence of Beta-lactamase enzyme
• Approximately 40-50% absorption with or without food

Dosage & Administration

• Usual course of treatment is 7 days, may be continued for up to 14 days if required
• Adult dosage: 200-400 mg daily according to severity of infection
• Recommended dosage for children: 8 mg/kg/day administered as a single dose or in two divided doses

Interaction

• Increases in prothrombin times have been noted in a few patients
• Care should be taken in patients receiving anticoagulant therapy

Contraindications

• Hypersensitivity to cephalosporin antibiotics

Side Effects

• Mild and self-limiting adverse reactions observed
• Frequent side-effects include diarrhea, nausea, abdominal pain
• Other side-effects include headache, dizziness, rash, pruritis, thrombocytopenia
• Mild transient change in liver and renal function tests observed

Pregnancy & Lactation

• No adequate and well-controlled studies in pregnant women
• Caution should be exercised when administered to a nursing woman

Precautions & Warnings

• Given with caution to patients with known hypersensitivity to other drugs
• Caution in penicillin-sensitive patients due to cross-allergenicity
• Caution in patients with markedly impaired renal function
• Treatment alters normal flora of the colon and may permit overgrowth of clostridia

Overdose Effects

• Gastric Lavage may be indicated; no specific antidote exists
• Not removed in significant quantities by hemodialysis or peritoneal dialysis
• Adverse reactions in healthy adult volunteers at doses up to 2 g did not differ from profile seen in patients treated at recommended doses

Therapeutic Class

• Third-generation Cephalosporins

Storage Conditions

• Keep below 30°C temperature, protected from light & moisture
• Keep out of the reach of children

Chemical Structure

• Molecular Formula: C16H15N5O7S2

Common Questions about Xylocef 200 mg Capsule

• Used to treat bacterial infection but not viral infections
• Side effects include diarrhea, abdominal pain, dizziness, rash
• Should be kept in a cool dry place and in its original pack
• Will not work for treating cold and flu
• No specific dietary instructions; continue normal diet unless advised otherwise

Related Brands

• Cefixime-A 400 mg (Capsule) - ad-din-pharmaceuticals-ltd
• Odacef DS 200 mg/5 ml (Powder for Suspension) - unimed-unihealth-pharmaceuticals-ltd
• Starcef DS 200 mg/5 ml (Powder for Suspension) - beacon-pharmaceuticals-plc
• Cosmoxim 200 mg (Capsule) - cosmo-pharma-laboratories-ltd
• Cosmoxim 200 mg (Capsule) - cosmo-pharma-laboratories-ltd