Duracef 25 mg/ml (Pediatric Drops)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefixime trihydrate |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Indications
Duracef is indicated for the treatment of Upper Respiratory Tract Infections, Lower Respiratory Tract Infections, Urinary Tract Infections, and other acute infections caused by susceptible microorganisms.
Pharmacology
Cefixime is a third generation semisynthetic cephalosporin antibiotic for oral administration. It is bactericidal against a broad spectrum of gram positive and gram negative bacteria at easily achievable plasma concentrations.
Dosage & Administration
- Adults and children over 10 years:
- Recommended dosage of 200-400 mg daily
- Usual course of treatment is 7 days
- Elderly: Same dose as recommended for adults with dosage adjustment in severe renal impairment
- Children:
- Recommended dosage for children is 8 mg/kg/day
- Specific daily doses based on age and weight
- Safety and efficacy not established in children aged less than 6 months
Interaction
Increases in prothrombin times may occur in patients receiving anticoagulant therapy.
Contraindications
Not to be used in patients with known hypersensitivity to cephalosporin antibiotics.
Side Effects
- Gastrointestinal disturbances:
- Diarrhea
- Nausea
- Abdominal pain
- Vomiting
- Flatulence
- Central nervous system:
- Headache
- Dizziness
- Hypersensitivity reactions:
- Rash
- Pruritis
- Urticaria
- Hematological and clinical chemistry:
- Thrombocytopenia
- Leukopenia
- Eosinophilia
- Miscellaneous:
- Genital pruritis
- Vaginitis
Pregnancy & Lactation
Use during pregnancy only if clearly needed, caution should be exercised when administered to a nursing woman.
Precautions & Warnings
- Hypersensitivity: Should be given with caution to patients who have shown hypersensitivity to other drugs.
- Renal function: Administered with caution in patients with markedly impaired renal function.
- Use in pregnancy and lactation: Not recommended unless considered essential by the physician
Overdose Effects
Gastric lavage may be indicated; no specific antidote exists. Not removed in significant quantities from circulation by hemodialysis or peritoneal dialysis.
Therapeutic Class
Third generation Cephalosporins
Storage Conditions
Keep below 30°C temperature, protected from light & moisture. Keep out of the reach of children.
Chemical Structure
- Molecular Formula: C16H15N5O7S2
- Chemical Structure: Cefixime Trihydrate
Common Questions
- Uses:
- Treatment of bacterial infections including Urinary Tract Infection, Tonsillitis, Pharyngitis, and Bronchitis
- Side Effects:
- Diarrhea
- Abdominal pain
- Swelling of the face, lips, hands, and feet
- Dizziness
- Indigestion
- Sore throat
- Storage and disposal: Keep in a cool dry place and in its original pack; proper disposal of expired and unused medications is important.
- Special dietary instruction: Continue normal diet unless advised otherwise by the doctor.
- Infant use: Safety not established for infants less than 6 months; consultation with a doctor is necessary.
- Interaction with other medications: Consult a doctor before concurrent use of other medications.
- Onset of action: Starts working soon after ingestion, full symptom relief may take a few days.
- Completing the course: Finish the full course of treatment even if feeling better to avoid antibiotic resistance.
- Alcohol consumption: Avoid consuming alcohol while taking Duracef.
- Safety measures:
- Do not skip any doses
- Take it with food to avoid an upset stomach
- Inform your doctor if you get a rash or have difficulty in breathing