Sanfix DS 200 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 280.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Nuvista pharma ltd
Also available as
Sanfix 200 mg capsule Sanfix 100 mg suspension Sanfix 400 mg capsule

Title

  • Sanfix DS 200 mg/5 ml Suspension

Categories

  • Medicine
  • Antibiotic
  • Oral Medication
  • Cephalosporin

Description

  • Orally active cephalosporin antibiotic
  • Bactericidal activity against Gram-positive and Gram-negative organisms
  • Indicated for acute infections caused by susceptible microorganisms
  • Highly stable in the presence of beta-lactamase enzymes
  • Broad-spectrum antibiotic
  • Third generation semisynthetic cephalosporin antibiotic
  • Bactericidal against broad spectrum of bacteria
  • Interferes in the synthesis of bacterial cell wall
  • Usual treatment course of 7-14 days
  • Dosage and administration varying by age and severity of infection
  • Pharmacokinetics unaffected by food intake
  • Contraindicated in individuals with known hypersensitivity to cephalosporins
  • Potential to increase prothrombin times in patients receiving anticoagulant therapy
  • Well tolerated with mostly mild and self-limiting adverse reactions
  • Storage at temperatures below 30°C, protected from light and moisture
  • Precautions advised for patients with hypersensitivity to other drugs
  • Caution recommended for penicillin-sensitive patients
  • Alters normal flora of colon and may result in antibiotic-associated diarrhea
  • Disposal of expired and unused medications necessary to avoid health problems
  • No specific antidote for overdose
  • No significant removal by hemodialysis or peritoneal dialysis
  • Chemical structure: C16H15N5O7S2
  • Chemical structure depicted in image
  • Commonly associated with diarrhoea and gastrointestinal disturbances
  • Potential side effects include headache, dizziness, nausea, abdominal pain, and dyspepsia
  • Allergies may manifest as rash, pruritis, urticaria, and drug fever

Indications

  • Treatment of upper respiratory tract infections (URTI)
  • Treatment of lower respiratory tract infections such as bronchitis
  • Treatment of urinary tract infections (cystitis, cystourethritis, pyelonephritis)
  • Demonstrated clinical efficacy against Streptococcus pneumonia, Streptococcus pyogenes, Escherichia coli, and other common pathogens
  • High stability in the presence of beta-lactamase enzymes

Mode of action

  • Bactericidal action against broad spectrum of gram positive and gram negative bacteria
  • Inhibition of bacterial cell wall synthesis
  • Stability in the presence of Beta-lactamase enzyme

Dosage and administration

  • Usual course of treatment is 7-14 days
  • Dosage varies by age and severity of infection
  • Absorption not significantly affected by food intake
  • Adult dosage range: 200-400 mg daily
  • Dosage adjustment advised in severe renal impairment
  • Recommended dosages for children based on age and body weight

Interaction

  • Potential to increase prothrombin times in some patients
  • Caution advised in patients receiving anticoagulant therapy

Contraindications

  • Contraindicated in patients with known hypersensitivity to cephalosporin antibiotics

Side effects

  • Commonly associated with gastrointestinal disturbances, including diarrhoea and stool changes
  • Frequent gastrointestinal side effects include nausea, abdominal pain, and dyspepsia
  • Occasional side effects include headache, dizziness, and hypersensitivity reactions
  • Rare hematological and clinical chemistry reactions reported

Pregnancy and lactation

  • Insufficient data on safety and efficacy in pregnant women
  • Caution recommended for use during pregnancy if clearly needed
  • Caution advised when administered to nursing women

Precautions and warnings

  • Caution advised for patients with hypersensitivity to other drugs
  • Partial cross-allergenicity between penicillins and cephalosporins documented
  • Potential for severe reactions in penicillin-sensitive patients
  • Caution advised in patients with markedly impaired renal function
  • Altered normal flora of the colon may result in antibiotic-associated diarrhea
  • Avoid use in pregnancy or nursing mothers unless considered essential by a physician

Overdose effects

  • Gastric Lavage may be indicated in cases of overdose
  • No specific antidote available
  • Not significantly removed by hemodialysis or peritoneal dialysis
  • Adverse reactions similar to those seen at recommended doses

Therapeutic class

  • Third generation Cephalosporins

Storage conditions

  • Storage below 30°C temperature
  • Protection from light and moisture
  • Keep out of the reach of children

Chemical structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure depicted in image

Common questions

  • What is Sanfix DS 200 mg/5 ml Syrup?
  • What are the uses of Sanfix DS 200 mg/5 ml Syrup?
  • What are the Side Effects of Sanfix DS 200 mg/5 ml Syrup?
  • What are the instructions for storage and disposal Sanfix DS 200 mg/5 ml Syrup?
  • Will Sanfix DS 200 mg/5 ml Syrup work for treating cold and flu?
  • Is there any special dietary instruction which I should follow?
  • Is Sanfix DS 200 mg/5 ml Syrup can be used to treat diarrhoea?
  • Is it safe to give Sanfix DS 200 mg/5 ml Syrup to infants?
  • Does Sanfix DS 200 mg/5 ml Syrup is a penicillin variant?
  • Does Sanfix DS 200 mg/5 ml Syrup cause loose-motion?
  • Is constipation associated with Sanfix DS 200 mg/5 ml Syrup?
  • Does Sanfix DS 200 mg/5 ml Syrup interact with contraception?
  • Can I take acetaminophen along with Sanfix DS 200 mg/5 ml Syrup?
  • How long does Sanfix DS 200 mg/5 ml Syrup take to work?
  • What if I do not get better after using Sanfix DS 200 mg/5 ml Syrup?
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