Onefix 400 mg (Capsule)
Unit Price: ৳ 50.00 (1 x 7: ৳ 350.00)
Strip Price: ৳ 350.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefixime trihydrate |
| Company | One pharma ltd |
| Also available as |
Indications
- Treatment of upper respiratory tract infections (URTI)
- Treatment of lower respiratory tract infections
- Treatment of urinary tract infections (UTI)
- Demonstrated efficacy against specific pathogens
- Stability in the presence of beta-lactamase enzymes
Pharmacology
- Third generation semisynthetic cephalosporin antibiotic
- Bactericidal against broad spectrum of bacteria
- Interferes in bacterial cell wall synthesis
- Stable in the presence of Beta-lactamase enzyme
- About 40-50% absorption with or without food
Dosage & Administration
- Usual 7-day treatment course, extendable to 14 days if necessary
- Recommended adult dosage of 200-400 mg daily for severity of infection
- Elderly patients may be given same dose as adults
- Recommended dosage for children based on age and weight
- Safe use in renal impairment
- Dose and regimen for patients maintained on chronic dialysis
Interaction
- Possible increase in prothrombin times in some patients receiving anticoagulant therapy
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Generally well tolerated
- Mild and self-limiting adverse reactions observed in clinical trials
- Frequent gastrointestinal disturbances
- Possible central nervous system effects
- Hypersensitivity reactions like rash, pruritus, urticaria
- Hematological and clinical chemistry effects including thrombocytopenia, leukopenia, and eosinophilia
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Caution for use during pregnancy only if clearly needed
- Unknown excretion in human milk, caution for use during nursing
Precautions & Warnings
- Caution in patients with hypersensitivity to other drugs
- Partial cross-allergenicity between penicillins and cephalosporins
- Administration with caution in patients with markedly impaired renal function
- Alteration of normal colon flora and potential for antibiotic-associated diarrhea
Overdose Effects
- Gastric Lavage may be indicated
- No specific antidote available
- Adverse reactions in healthy volunteers at doses up to 2 g did not differ from recommended doses profile
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Keep below 30°C temperature
- Protection from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C16H15N5O7S2
Common Questions about Onefix 400 mg Capsule
- Description of medication and its uses
- List of common side effects
- Instructions for storage and disposal
- Information on treating cold and flu
- Special dietary instructions
- Use in infants, constipation, and diarrhoea
- Interaction with contraception and acetaminophen
- Onset of action and monitoring for improvement
- Quick tips for usage