Onefix 100 mg/5 ml (Powder for Suspension)

30 ml bottle: ৳ 135.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company One pharma ltd
Also available as
Onefix 200 mg capsule Onefix 400 mg capsule

Product title

  • Onefix 100 mg/5 ml Suspension

Pharmacological class

  • Third generation Cephalosporins

Indications

  • Upper Respiratory Tract Infections (URTI)
  • Lower Respiratory Tract Infections
  • Urinary Tract Infections

Bactericidal activity

  • Marked in-vitro bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms

Bacterial susceptibility

  • Clinical efficacy against Streptococcus pneumonia, Streptococcus pyogenes, Escherichia coli, Proteus mirabilis, Klebsiella species, Haemophilus influenzae, Moraxella catarrhalis, Enterobacter species

Mode of action

  • Interferes in the synthesis of bacterial cell wall
  • Highly stable in the presence of Beta-lactamase enzyme

Absorption

  • 40% to 50% whether administered with or without food

Dosage and administration

  • Usual course of treatment is 7 days
  • Recommended adult dosage is 200-400 mg daily
  • Recommended dosage for children is 8 mg/kg/day
  • Dosage in Renal Impairment guidelines

Interaction

  • Increases in prothrombin times have been noted in some patients
  • Care should be taken in patients receiving anticoagulant therapy

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side effects

  • Diarrhoea
  • Stool changes
  • Nausea
  • Abdominal pain
  • Dyspepsia
  • Vomiting
  • Flatulence
  • Headache
  • Dizziness
  • Rash
  • Pruritis
  • Urticaria
  • Drug fever
  • Thrombocytopenia
  • Leukopenia
  • Eosinophilia
  • Genital pruritis
  • Vaginitis

Pregnancy and lactation

  • Caution recommended during pregnancy
  • Caution should be exercised when administered to a nursing woman

Precautions and warnings

  • Given with caution to patients who have shown hypersensitivity to other drugs
  • Cautious use for penicillin-sensitive patients
  • Administered with caution in patients with markedly impaired renal function
  • Use in pregnancy and lactation precautions

Overdose effects

  • Gastric Lavage may be indicated
  • No specific antidote exists
  • Not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysis

Storage conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure: Cefixime Trihydrate

Commonly asked questions

  • What is Onefix 100 mg/5 ml Syrup?
  • What are the uses of Onefix 100 mg/5 ml Syrup?
  • What are the Side Effects of Onefix 100 mg/5 ml Syrup?
  • What are the instructions for storage and disposal of Onefix 100 mg/5 ml Syrup?
  • Will Onefix 100 mg/5 ml Syrup work for treating cold and flu?
  • Is there any special dietary instruction which I should follow?
  • Is Onefix 100 mg/5 ml Syrup can be used to treat diarrhoea?
  • Is it safe to give Onefix 100 mg/5 ml Syrup to infants?
  • Does Onefix 100 mg/5 ml Syrup is a penicillin variant?
  • Does Onefix 100 mg/5 ml Syrup cause loose-motion?
  • Is constipation associated with Onefix 100 mg/5 ml Syrup?
  • Does Onefix 100 mg/5 ml Syrup interact with contraception?
  • Can I take acetaminophen along with Onefix 100 mg/5 ml Syrup?
  • How long does Onefix 100 mg/5 ml Syrup take to work?
  • What if I do not get better after using Onefix 100 mg/5 ml Syrup?
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