Orbixim 100 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 160.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Orbit pharmaceuticals ltd
Also available as
Orbixim 200 mg capsule

Title

Orbixim 100 mg/5 ml Suspension

Categories

  • Antibiotic
  • Cephalosporin
  • Medication
  • Pharmacology

Description

Orbixim is an orally active cephalosporin antibiotic with marked in-vitro bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms. It is indicated for the treatment of upper respiratory tract infections, lower respiratory tract infections, urinary tract infections, and more. The product is highly stable in the presence of beta-lactamase enzymes. It functions by interfering in the synthesis of bacterial cell wall and is bactericidal against a broad spectrum of bacteria at easily achievable plasma concentrations.

Dimensions

N/A

ColorOptions

  • N/A

Functions

  • Treats upper respiratory tract infections
  • Treats lower respiratory tract infections
  • Treats urinary tract infections
  • Prevents bacterial cell wall formation

Materials

  • N/A

TechnicalSpecifications

  • Molecular Formula: C16H15N5O7S2

DesignElements

  • Chemical Structure Image

UsabilityFeatures

  • Orally active
  • Highly stable in the presence of beta-lactamase enzymes
  • Absorption not significantly modified by the presence of food
  • Recommended adult dosage of 200-400 mg daily
  • Dosage recommended for children based on age and weight
  • Caution advised for patients with hypersensitivity to other drugs
  • Caution advised for penicillin-sensitive patients
  • Caution advised for patients with markedly impaired renal function
  • Storage below 30°C temperature, protected from light & moisture

Indication

  • Marked in-vitro bactericidal activity
  • Effective against a wide variety of Gram-positive and Gram-negative organisms
  • Indicated for upper respiratory tract infections (e.g., otitis media)
  • Indicated for lower respiratory tract infections (e.g., bronchitis)
  • Indicated for urinary tract infections (e.g., cystitis, cystourethritis, pyelonephritis)

Pharmacology

  • Third generation semisynthetic cephalosporin antibiotic for oral administration
  • Bactericidal against a broad spectrum of gram-positive and gram-negative bacteria
  • Interferes with the synthesis of bacterial cell wall
  • Highly stable in the presence of Beta-lactamase enzyme
  • Absorption of about 40% to 50% whether administered with or without food

DosageAndAdministration

  • Usual course of treatment is 7 days, may be continued for up to 14 days if required
  • Recommended adult dosage: 200-400 mg daily
  • Recommended children dosage: 8 mg/kg/day
  • Dosage in renal impairment should be adjusted based on creatinine clearance

Interaction

  • Increases in prothrombin times noted in a few patients
  • Care should be taken in patients receiving anticoagulant therapy

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

SideEffects

  • Most adverse reactions observed in clinical trials were mild and self-limiting
  • Frequent side-effects include diarrhea and stool changes
  • Other side-effects include gastrointestinal disturbances, central nervous system effects, hypersensitivity reactions, hematological and clinical chemistry changes, and miscellaneous reactions

PregnancyAndLactation

  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy only if clearly needed
  • Caution should be exercised when administered to a nursing woman

PrecautionsAndWarnings

  • Given with caution to patients who have shown hypersensitivity to other drugs
  • Given with caution to penicillin-sensitive patients
  • Given with caution in patients with markedly impaired renal function
  • Use in pregnancy and lactation should be with caution

OverdoseEffects

  • Gastric Lavage may be indicated
  • No specific antidote exists
  • Orbixim is not removed in significant quantities by hemodialysis or peritoneal dialysis

CommonlyAskedQuestions

  • What is Orbixim 100 mg/5 ml Syrup?
  • What are the uses of Orbixim 100 mg/5 ml Syrup?
  • What are the Side Effects of Orbixim 100 mg/5 ml Syrup?
  • What are the instructions for storage and disposal Orbixim 100 mg/5 ml Syrup?
  • Will Orbixim 100 mg/5 ml Syrup work for treating cold and flu?
  • Is there any special dietary instruction which I should follow?
  • Is Orbixim 100 mg/5 ml Syrup can be used to treat diarrhoea?
  • Is it safe to give Orbixim 100 mg/5 ml Syrup to infants?
  • Does Orbixim 100 mg/5 ml Syrup is a penicillin variant?
  • Does Orbixim 100 mg/5 ml Syrup cause loose-motion?
  • Is constipation associated with Orbixim 100 mg/5 ml Syrup?
  • Does Orbixim 100 mg/5 ml Syrup interact with contraception?
  • Can I take acetaminophen along with Orbixim 100 mg/5 ml Syrup?
  • How long does Orbixim 100 mg/5 ml Syrup take to work?
  • What if I do not get better after using Orbixim 100 mg/5 ml Syrup?
  • Quick Tips

DrugClasses

  • Third generation Cephalosporins

StorageConditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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