Trifix 400 mg (Capsule)
Unit Price: ৳ 55.00 (2 x 4: ৳ 440.00)
Strip Price: ৳ 220.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefixime trihydrate |
| Company | Pacific pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of Upper Respiratory Tract Infections (URTI)
- Treatment of Lower Respiratory Tract Infections
- Treatment of Urinary Tract Infections
- Clinical efficacy against Streptococcus pneumonia
- Clinical efficacy against Escherichia coli
- Clinical efficacy against Proteus mirabilis
- Clinical efficacy against Haemophilus influenzae
- Bactericidal activity against Gram-positive organisms
- Bactericidal activity against Gram-negative organisms
- Stability in the presence of beta-lactamase enzymes
Pharmacology
- Third generation semisynthetic cephalosporin antibiotic
- Bactericidal against a broad spectrum of bacteria
- Interferes with synthesis of bacterial cell wall
- Highly stable in the presence of Beta-lactamase enzyme
- Absorption unaffected by the presence of food
Dosage & Administration
- Usual course of treatment is 7 days
- Dosage varies for adults based on severity of infection
- Special dosage guidelines for children
- Dosage adjustment in severe renal impairment
- Recommendations for dosage in typhoid
- Caution about altered normal colon flora due to antibiotic use
Interaction
- Potential increase in prothrombin times in some patients
- Caution required in patients receiving anticoagulant therapy
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Mild and self-limiting adverse reactions
- Frequent gastrointestinal disturbances
- Occasional central nervous system effects
- Possible hypersensitivity reactions
- Reported hematological and clinical chemistry side effects
- Occasional genital and miscellaneous reactions
Pregnancy & Lactation
- Limited data on use in pregnant women
- Caution advised during pregnancy if clearly needed
- Caution advised during nursing
Precautions & Warnings
- Caution in patients with hypersensitivity to other drugs
- Partial cross-allergenicity with penicillins
- Administration caution in markedly impaired renal function
Overdose Effects
- Gastric Lavage may be indicated
- No specific antidote exists
- Not removed in significant quantities by dialysis
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C16H15N5O7S2
Common Questions
- What is Trifix 400 mg Capsule?
- Uses of Trifix 400 mg Capsule
- Side Effects of Trifix 400 mg Capsule
- Instructions for storage and disposal of Trifix 400 mg Capsule
- Suitability for treating cold and flu
- Special dietary instructions
- Use for treating diarrhoea
- Safety for infants
- Comparison with penicillin variant
- Loose-motion and constipation effects
- Interactions with contraception and acetaminophen
- Duration of action
- Next steps if no improvement
- Quick Tips for usage