Fixim 200 mg (Capsule)
Unit Price: ৳ 30.20 (4's pack: ৳ 120.80)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefixime trihydrate |
| Company | Reman drug laboratories ltd |
| Also available as |
Indications
- Treatment of Upper Respiratory Tract Infections (URTI)
- Treatment of Lower Respiratory Tract Infections
- Treatment of Urinary Tract Infections
- Clinical efficacy against Streptococcus pneumonia
- Clinical efficacy against Escherichia coli
- High stability in the presence of beta-lactamase enzymes
Pharmacology
- Third generation semisynthetic cephalosporin antibiotic
- Bactericidal against a broad spectrum of gram positive and gram negative bacteria
- Interferes in the synthesis of bacterial cell wall
- Highly stable in the presence of Beta-lactamase enzyme
- Approximately 40% to 50% absorption rate
- Oral administration
Dosage & Administration
- Usual course of treatment is 7 days
- Recommended adult dosage is 200-400 mg daily
- Dosage adjustment in severe renal impairment
- Dosage for children based on age and weight
- Can be administered with or without food
Interaction
- Potential increase in prothrombin times in some patients
- Careful use in patients receiving anticoagulant therapy
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Commonly reported adverse reactions
- Mild and self-limiting nature of observed reactions
- Gastrointestinal disturbances
- Central nervous system effects
- Hypersensitivity reactions
- Hematological and clinical chemistry effects
- Mild transient changes in liver and renal function tests
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Caution advised for use during pregnancy and lactation
- Potential excretion in human milk
Precautions & Warnings
- Caution for patients with hypersensitivity to other drugs
- Partial cross-allergenicity between penicillins and cephalosporins
- Careful use in patients with markedly impaired renal function
- Alteration of normal flora of the colon with broad spectrum antibiotics
- Potential for Clostridium difficile overgrowth
Overdose Effects
- Gastric Lavage may be indicated
- No specific antidote exists
- Not removed significantly by hemodialysis or peritoneal dialysis
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C16H15N5O7S2
- Chemical Structure Image: Link to structure image
Common Questions
- Definition and usage of Fixim 200 mg Capsule
- Uses of Fixim 200 mg Capsule
- Commonly reported side effects of Fixim 200 mg Capsule
- Instructions for storage and disposal of Fixim 200 mg Capsule
- Ineffectiveness of Fixim 200 mg Capsule for cold and flu treatment
- No need for special dietary instruction
- Inappropriateness of using Fixim 200 mg Capsule for treating diarrhea
- Safety concerns for using Fixim 200 mg Capsule for infants
- Differentiation of Fixim 200 mg Capsule from penicillin variants
- Effect of Fixim 200 mg Capsule on contraception
- Possible interactions with acetaminophen
- Duration for Fixim 200 mg Capsule to start working
- Instructions if symptoms do not improve after using Fixim 200 mg Capsule
- Quick tips for patients prescribed Fixim 200 mg Capsule