Fixim 200 mg (Capsule)

Unit Price: ৳ 30.20 (4's pack: ৳ 120.80)

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Reman drug laboratories ltd
Also available as
Fixim 100 mg suspension

Indications

  • Treatment of Upper Respiratory Tract Infections (URTI)
  • Treatment of Lower Respiratory Tract Infections
  • Treatment of Urinary Tract Infections
  • Clinical efficacy against Streptococcus pneumonia
  • Clinical efficacy against Escherichia coli
  • High stability in the presence of beta-lactamase enzymes

Pharmacology

  • Third generation semisynthetic cephalosporin antibiotic
  • Bactericidal against a broad spectrum of gram positive and gram negative bacteria
  • Interferes in the synthesis of bacterial cell wall
  • Highly stable in the presence of Beta-lactamase enzyme
  • Approximately 40% to 50% absorption rate
  • Oral administration

Dosage & Administration

  • Usual course of treatment is 7 days
  • Recommended adult dosage is 200-400 mg daily
  • Dosage adjustment in severe renal impairment
  • Dosage for children based on age and weight
  • Can be administered with or without food

Interaction

  • Potential increase in prothrombin times in some patients
  • Careful use in patients receiving anticoagulant therapy

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Commonly reported adverse reactions
  • Mild and self-limiting nature of observed reactions
  • Gastrointestinal disturbances
  • Central nervous system effects
  • Hypersensitivity reactions
  • Hematological and clinical chemistry effects
  • Mild transient changes in liver and renal function tests

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Caution advised for use during pregnancy and lactation
  • Potential excretion in human milk

Precautions & Warnings

  • Caution for patients with hypersensitivity to other drugs
  • Partial cross-allergenicity between penicillins and cephalosporins
  • Careful use in patients with markedly impaired renal function
  • Alteration of normal flora of the colon with broad spectrum antibiotics
  • Potential for Clostridium difficile overgrowth

Overdose Effects

  • Gastric Lavage may be indicated
  • No specific antidote exists
  • Not removed significantly by hemodialysis or peritoneal dialysis

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

    • Molecular Formula: C16H15N5O7S2
    • Chemical Structure Image: Link to structure image

Common Questions

  • Definition and usage of Fixim 200 mg Capsule
  • Uses of Fixim 200 mg Capsule
  • Commonly reported side effects of Fixim 200 mg Capsule
  • Instructions for storage and disposal of Fixim 200 mg Capsule
  • Ineffectiveness of Fixim 200 mg Capsule for cold and flu treatment
  • No need for special dietary instruction
  • Inappropriateness of using Fixim 200 mg Capsule for treating diarrhea
  • Safety concerns for using Fixim 200 mg Capsule for infants
  • Differentiation of Fixim 200 mg Capsule from penicillin variants
  • Effect of Fixim 200 mg Capsule on contraception
  • Possible interactions with acetaminophen
  • Duration for Fixim 200 mg Capsule to start working
  • Instructions if symptoms do not improve after using Fixim 200 mg Capsule
  • Quick tips for patients prescribed Fixim 200 mg Capsule

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