Goutex 100 mg (Tablet)
Unit Price: ৳ 4.02 (10 x 10: ৳ 402.00)
Strip Price: ৳ 40.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Allopurinol |
| Company | Biopharma limited |
| Also available as |
Indications
- Reduction of urate/uric acid formation
- Management of gouty arthritis
- Treatment of 2,8-dihydroxyadenine (2,8-DHA) renal stones
- Management of calcium oxalate renal stones
- Hyperuricosuria management
Pharmacology
- Xanthine oxidase inhibitor
- Oral administration
- Reduction of uric acid production
- Plasma half-life of 1-2 hours
- Approximately 90% absorption from GI tract
Dosage & Administration
- Initial adult dosage of 100 mg/day
- Dosage escalation based on serum urate response
- Specific dosage schedules for different conditions
- Dosage adjustment in renal impairment
- Maximum children's dosage of 400 mg daily
Interaction
- Interactions with 6-mercaptopurine, azathioprine, vidarabine, theophylline, ampicillin, amoxicillin, ciclosporin
Contraindications
- Known hypersensitivity to allopurinol
Side Effects
- Rashes
- Gastrointestinal disorders
- Malaise
- Headache
- Visual and test disturbances
- Hepatotoxicity
- Neuropathy
- Blood disorders
Pregnancy & Lactation
- Use only if no safer alternative
- Inadequate evidence of safety in human pregnancy
- No data on effects on breast-fed baby
Precautions & Warnings
- Immediate withdrawal on skin rash or sensitivity
- Reduced doses for hepatic or renal impairment patients
- Caution in patients with hypertension or cardiac insufficiency
Overdose Effects
- Reported ingestion of up to 22.5g without adverse effect
- Symptoms including nausea, vomiting, diarrhea, dizziness
- Facilitation of excretion with hydration
- Potential use of hemodialysis
Therapeutic Class
- Drugs used in Gout
Storage Conditions
- Temperature below 30°C
- Protection from light and moisture
- Keep out of reach of children