Cef-3 25 mg/ml (Pediatric Drops)

21 ml bottle: ৳ 100.30

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Square pharmaceuticals plc
Also available as
Cef 3 200 mg capsule Cef 3 ds 400 mg capsule Cef 3 100 mg suspension Cef 3 forte 200 mg suspension Cef 3 max 100 mg pediatric drop

Title

  • Cef-3 25 mg/ml Pediatric Drops

Categories

  • Medicine
  • Antibiotic
  • Pediatric Medicine

Description

  • Orally active cephalosporin antibiotic
  • Bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms
  • Indicated for upper respiratory tract infections (URTI)
  • Indicated for lower respiratory tract infections
  • Indicated for urinary tract infections
  • High stability in the presence of beta-lactamase enzymes
  • Bactericidal against a broad spectrum of gram-positive and gram-negative bacteria
  • Interferes in the synthesis of bacterial cell wall
  • Usual course of treatment is 7 days
  • Can be continued for up to 14 days if required
  • Recommended adult dosage is 200-400 mg daily
  • Recommended dosage for children is 8 mg/kg/day
  • Interaction with anticoagulant therapy
  • Contraindicated in patients with known hypersensitivity to cephalosporin antibiotics
  • Mild and self-limiting adverse reactions observed in clinical trials
  • Caution in patients with hypersensitivity to other drugs
  • Caution in penicillin-sensitive patients
  • Caution in patients with markedly impaired renal function
  • Alters the normal flora of the colon
  • Gastric lavage may be indicated in case of overdose
  • No specific antidote for overdose
  • Kept below 30°C temperature, protected from light and moisture
  • Chemical structure: C16H15N5O7S2
  • Therapeutic class: Third generation cephalosporins

Indications

  • Treatment of upper respiratory tract infections (URTI) caused by susceptible microorganisms
  • Treatment of lower respiratory tract infections, e.g. bronchitis
  • Treatment of urinary tract infections

Pharmacology

  • Third generation semisynthetic cephalosporin antibiotic for oral administration
  • Bactericidal against a broad spectrum of gram-positive and gram-negative bacteria
  • Kills bacteria by interfering in the synthesis of bacterial cell wall
  • High stability in the presence of beta-lactamase enzyme
  • Absorption of about 40% to 50% whether administered with or without food

Dosage and administration

  • Usual course of treatment is 7 days
  • May be continued for up to 14 days if required
  • Recommended adult dosage is 200-400 mg daily
  • Recommended dosage for children is 8 mg/kg/day
  • Dosage in renal impairment

Interaction

  • Increases in prothrombin times noted in a few patients
  • Care should be taken in patients receiving anticoagulant therapy

Contraindications

  • Known hypersensitivity to cephalosporin antibiotics

Side effects

  • Majority of adverse reactions observed in clinical trials were mild and self-limiting
  • Gastrointestinal disturbances
  • Diarrhoea and stool changes
  • Nausea, abdominal pain, dyspepsia, vomiting, flatulence
  • Headache and dizziness
  • Allergies in the form of rash, pruritis, urticaria, drug fever, arthralgia
  • Thrombocytopenia, leukopenia, eosinophilia
  • Mild transient change in liver and renal function tests
  • Genital pruritis and vaginitis

Pregnancy and lactation

  • No adequate and well-controlled studies in pregnant women
  • Caution should be exercised when administered to a nursing woman

Precautions and warnings

  • Given with caution to patients who have shown hypersensitivity to other drugs
  • Caution in penicillin-sensitive patients
  • Caution in patients with markedly impaired renal function
  • Treatment with broad-spectrum antibiotics alters the normal flora of the colon

Overdose effects

  • Gastric lavage may be indicated
  • No specific antidote exists
  • Not removed in significant quantities by hemodialysis or peritoneal dialysis

Storage conditions

  • Keep below 30°C temperature
  • Protected from light and moisture
  • Keep out of the reach of children

Chemical structure

    • Molecular formula: C16H15N5O7S2
    • Chemical structure image: https://medex.com.bd/storage/res/g-res-217-cefixime-trihydrate-chemical-structure-3Mg9h2a2PuSZaJk4Uj0Z.svg

Commonly asked questions

  • What is Cef-3 25 mg/ml Drops?
  • What are the uses of Cef-3 25 mg/ml Drops?
  • What are the side effects of Cef-3 25 mg/ml Drops?
  • What are the instructions for storage and disposal of Cef-3 25 mg/ml Drops?
  • Will Cef-3 25 mg/ml Drops work for treating cold and flu?
  • Is there any special dietary instruction which I should follow?
  • Is Cef-3 25 mg/ml Drops can be used to treat diarrhoea?
  • Is it safe to give Cef-3 25 mg/ml Drops to infants?
  • Does Cef-3 25 mg/ml Drops is a penicillin variant?
  • Does Cef-3 25 mg/ml Drops cause loose-motion?
  • Is constipation associated with Cef-3 25 mg/ml Drops?
  • Does Cef-3 25 mg/ml Drops interact with contraception?
  • Can I take acetaminophen along with Cef-3 25 mg/ml Drops?
  • How long does Cef-3 25 mg/ml Drops take to work?
  • What if I do not get better after using Cef-3 25 mg/ml Drops?
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