Ometid 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 6.00 (9 x 10: ৳ 540.00)
Strip Price: ৳ 60.00
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Opsonin pharma ltd |
Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of antisecretory effect within one hour
- Maximum effect occurring within two hours
- Inhibition of secretion lasting up to 72 hours
- Gradual return of secretory activity over 3 to 5 days upon discontinuation
Dosage
- Dosage for benign gastric and duodenal ulcer
- Dosage for NSAID-associated duodenal or gastric ulcer
- Dosage for gastro-esophageal reflux disease
- Dosage for long-term management of acid reflux disease
- Dosage for acid-related dyspepsia
- Dosage for prophylaxis of acid aspiration
- Dosage for Zollinger-Ellison syndrome
- Dosage for Helicobacter pylori eradication regimen in peptic ulcer disease
- Pediatric dosage for severe ulcerating reflux esophagitis
Administration
- Direction for use of IV Injection
- Direction for use of IV Infusion
- Instructions for reconstitution and administration of IV injection
- Instructions for IV infusion preparation and administration
- Caution for co-administration with other drugs in the same infusion set
Interaction
- Effect on absorption of ketoconazole
- Metabolism in the liver through cytochrome P450
- Potential delay in the elimination of diazepam, phenytoin, and warfarin
- Monitoring and dose adjustment recommendations for warfarin or phenytoin
- Increased plasma concentrations during concomitant administration with clarithromycin
- No evidence of interaction with certain drugs such as phenacetin, theophylline, caffeine, etc.
Contraindications
- Known hypersensitivity to Omeprazole
- Exclusion of malignancy before treatment in suspected gastric ulcer
Side Effects
- Skin rash, urticaria, and pruritus
- Photosensitivity, bullous eruption, and erythema multiforme
- Diarrhea and headache
- Gastrointestinal reactions such as constipation, nausea/vomiting, flatulence, and abdominal pain
- Neurological symptoms like paraesthesia, dizziness, and vertigo
- Mental confusion, agitation, and depression
- Musculoskeletal symptoms like arthritic and myalgic symptoms
- Reports of blurred vision, taste disturbance, and peripheral edema
- Hepatic reactions and increased liver enzymes
Pregnancy & Lactation
- Results from prospective epidemiological studies
- Use during pregnancy without observed adverse effects
- No information available on passage into breast milk or effects on neonate
- Recommendation for discontinuation of breastfeeding if essential use is considered
Precautions & Warnings
- Avoid concomitant use of clopidogrel and Ometid
- Association between PPI therapy and increased risk for osteoporosis-related fractures
- Occurrence of atrophic gastritis in long-term treatment
- Potential for methotrexate toxicities with concomitant PPI use
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children
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