Ometop 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 4.00 (30's pack: ৳ 120.00)
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Novus pharmaceuticals ltd |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase enzyme system
- Onset of antisecretory effect within one hour
- Maximum effect occurs within two hours
- Inhibition of secretion lasts up to 72 hours
Dosage
- Different dosages for different indications
- Dosage range: 10-120 mg daily
Administration
- Oral and IV administration
- Directions for IV injection and IV infusion
Interaction
- Impact on absorption of ketoconazole
- Metabolism in the liver through cytochrome P450
- Interactions with diazepam, phenytoin, warfarin, clarithromycin
- No interaction with phenacetin, theophylline, caffeine, etc.
Contraindications
- Known hypersensitivity to omeprazole
- Suspicion of gastric ulcer should exclude malignancy before treatment
Side Effects
- Mild and reversible adverse reactions
- Skin rash, urticaria, pruritus, photosensitivity
- Diarrhoea, headache, constipation, nausea/vomiting
- Dizziness, somnolence, insomnia, vertigo
Pregnancy & Lactation
- No adverse effects on pregnancy or fetus/newborn child
- No information on passage into breast milk
- Use in children & adolescents not established
Precautions & Warnings
- Avoid concomitant use with clopidogrel
- Risk of osteoporosis-related fractures
- Atrophic gastritis with long-term use
- Potential interaction with methotrexate
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
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