Omidex 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.00 (100's pack: ৳ 500.00)
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Modern pharmaceuticals ltd |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of the antisecretory effect within one hour
- Maximum effect occurring within two hours
- Inhibition of secretion lasting up to 72 hours
- Gradual return of secretory activity over 3 to 5 days after discontinuation
Dosage
- 20 mg once daily for benign gastric and duodenal ulcer
- 10-20 mg daily for long-term management of acid reflux disease
- 40 mg on the preceding evening, then 40 mg 2-6 hours before surgery for prophylaxis of acid aspiration
- 20 mg twice daily in association with antimicrobial agents for Helicobacter pylori eradication regimen
- Intravenous injection for various conditions
Administration
- IV Injection for prophylaxis and specific syndromes
- IV Infusion over a period of 20-30 minutes or more
Interaction
- Absorption of ketoconazole may be reduced during Omidex treatment
- May delay the elimination of diazepam, phenytoin, and warfarin
- Increased plasma concentrations during concomitant administration
- No evidence of interaction with various drugs and substances
Contraindications
- Known hypersensitivity to Omeprazole
- Suspicion of gastric ulcer should exclude the possibility of malignancy before treatment
Side Effects
- Skin rash, urticaria, and pruritus
- Photosensitivity, bullous eruption, and erythema multiforme
- Diarrhoea, headache, constipation, nausea/vomiting, and abdominal pain
- Dry mouth, stomatitis, and candidiasis
- Dizziness, light headedness, and feeling faint
- Somnolence, insomnia, and vertigo
- Reversible mental confusion, agitation, depression, and hallucinations
- Arthritic and myalgic symptoms
- Various isolated cases of adverse effects
Pregnancy & Lactation
- No adverse effects on pregnancy or the health of the fetus/newborn child
- Use during pregnancy indicated
- No information available on the passage into breast milk or its effects on the neonate
- Discontinue breast-feeding if essential use of Omeprazole is considered
Precautions & Warnings
- Avoid concomitant use of clopidogrel
- Increased risk for osteoporosis-related fractures
- Occasional atrophic gastritis in gastric corpus biopsies from long-term treatment
- Caution with concomitant use of PPIs with methotrexate
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Related Brands
- Anasec 20 mg (Capsule (Enteric Coated)) - novo-healthcare-and-pharma-ltd
- Anasec 40 mg/vial (IV Injection) - novo-healthcare-and-pharma-ltd
- Aspra 20 mg (Capsule (Enteric Coated)) - apex-pharmaceuticals-ltd
- AU-20 20 mg (Capsule (Enteric Coated)) - decent-pharma-laboratories-ltd
- Aumi 20 mg (Capsule (Enteric Coated)) - hudson-pharmaceuticals-ltd