Cefteria 400 mg (Capsule)
Unit Price: ৳ 120.00 (2 x 5: ৳ 1,200.00)
Strip Price: ৳ 600.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftibuten dihydrate |
| Company | Aci limited |
| Also available as |
Indications
- Treatment of mild-to-moderate infections caused by susceptible strains of specific microorganisms
- Acute Bacterial Exacerbations of Chronic Bronchitis
- Acute Bacterial Otitis Media
- Pharyngitis and Tonsillitis
Pharmacology
Ceftibuten is a semi-synthetic Cephalosporin antibiotic for oral administration, exerting bactericidal action by binding to essential target proteins of the bacterial cell wall.
Dosage & Administration
- Otitis Media Adult Dosage: 400 mg orally every 24 hours for 10 days
- Otitis Media Pediatric Dosage: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
- Tonsillitis/Pharyngitis Adult Dosage: 400 mg orally every 24 hours for 10 days
- Tonsillitis/Pharyngitis Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
- Bronchitis Adult Dosage: 400 mg orally every 24 hours for 10 days
- Bronchitis Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 10 days
- Cystitis Adult Dosage: 400 mg orally every 24 hours for 7 days
- Cystitis Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 7 days
- Pneumonia Adult Dosage: 200 mg orally every 12 hours for 7 to 14 days
- Pneumonia Pediatric Dosage: >12 years: 200 mg orally every 12 hours for 7 to 14 days
- Sinusitis Adult Dosage: 400 mg orally every 24 hours for 10 to 14 days
- Sinusitis Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 10 to 14 days
- Urinary Tract Infection Adult Dosage: 400 mg orally every 24 hours for 10 days
- Urinary Tract Infection Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
Interaction
- Theophylline & Antacid do not alter the pharmacokinetic profile of Cefteria
- Ranitidine increases the Cmax & AUC of Cefteria
Contraindications
Ceftibuten is contraindicated in patients with known allergy to the cephalosporin group of antibiotics.
Side Effects
- Nausea
- Headache
- Diarrhea
- Dyspepsia
- Dizziness
- Abdominal Pain
- Vomiting
Pregnancy & Lactation
- Pregnancy Category B
- Use in pregnancy only when benefit outweighs the risk
- Caution in nursing women due to unknown excretion in human milk
Precautions & Warnings
- Prolonged treatment may result in the emergence of resistant organisms
- Dose adjustment may be necessary in patients with varying degrees of renal insufficiency
- Cautious use in individuals with a history of gastrointestinal disease, particularly colitis
Use in Special Populations
- Renal Impairment:
- CrCl 5 to 29 ml/min: 2.25 mg/kg or 100 mg orally once a day
- CrCl 30 to 49 ml/min: 4.5 mg/kg or 200 mg orally once a day
- Hepatic Impairment: Dose adjustment is not necessary
Therapeutic Class
Third generation Cephalosporins
Reconstitution
- Reconstitution process with purified water and granules
- Prepared suspension to be consumed within 14 days of preparation if kept in a refrigerator
- Shake the bottle well each time before use
Storage Conditions
- Store below 25°C, protected from light and moisture
- Suspension may be used for 14 days while stored at 2°C to 8°C
- Keep out of reach of children