Zoventa 200 mg (Capsule)
Unit Price: ৳ 78.33 (2 x 6: ৳ 940.00)
Strip Price: ৳ 470.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftibuten dihydrate |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of acute bacterial exacerbations of chronic bronchitis
- Treatment of acute bacterial otitis media
- Treatment of pharyngitis and tonsillitis
Pharmacology
- Cephalosporin antibiotic for oral administration
- Bactericidal action by binding to essential target proteins of the bacterial cell wall
- Inhibition of cell-wall synthesis
Dosage & Administration
- Otitis Media:
- Adult dosage: 400 mg orally every 24 hours for 10 days
- Pediatric dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
- Tonsillitis/Pharyngitis:
- Adult dosage: 400 mg orally every 24 hours for 10 days
- Pediatric dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
- Bronchitis:
- Adult dosage: 400 mg orally every 24 hours for 10 days
- Pediatric dosage: >12 years: 400 mg orally every 24 hours for 10 days
- Cystitis:
- Adult dosage: 400 mg orally every 24 hours for 7 days
- Pediatric dosage: >12 years: 400 mg orally every 24 hours for 7 days
- Pneumonia:
- Adult dosage: 200 mg orally every 12 hours for 7 to 14 days
- Pediatric dosage: >12 years: 200 mg orally every 12 hours for 7 to 14 days
- Sinusitis:
- Adult dosage: 400 mg orally every 24 hours for 10 to 14 days
- Pediatric dosage: >12 years: 400 mg orally every 24 hours for 10 to 14 days
- Urinary tract Infection:
- Adult dosage: 400 mg orally every 24 hours for 10 days
- Pediatric dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
Interaction
- Theophylline & Antacid do not alter the pharmacokinetic profile of the medication
- Ranitidine increases the Cmax & AUC of the medication
Contraindications
- Known allergy to the cephalosporin group of antibiotics
Side Effects
- Nausea
- Headache
- Diarrhea
- Dyspepsia
- Dizziness
- Abdominal pain
- Vomiting
Pregnancy & Lactation
- Pregnancy Category B
- Caution should be exercised when administered to nursing women
Precautions & Warnings
- Prolonged treatment may result in the possible emergence and overgrowth of resistant organisms
- Careful observation of the patient is essential
- Dose may require adjustment in patients with varying degrees of renal insufficiency
- Caution should be exercised when prescribed to individuals with a history of gastrointestinal disease, particularly colitis
Use in Special Populations
- Renal Impairment:
- CrCl 5 to 29 ml/min: 2.25 mg/kg or 100 mg orally once a day
- CrCl 30 to 49 ml/min: 4.5 mg/kg or 200 mg orally once a day
- Hepatic Impairment: Dose adjustment is not necessary
Therapeutic Class
Third generation Cephalosporins
Reconstitution
- The small bottle contains purified water and large bottle contains granules
- Prepared suspension to be consumed within 14 days of preparation if kept in a refrigerator
- Shake the bottle well each time before use
Storage Conditions
- Store below 25°C, protected from light and moisture
- After reconstitution, the suspension may be used for 14 days while stored at 2° to 8°C
- Keep out of reach of children