Zoventa 400 mg (Capsule)
Unit Price: ৳ 120.00 (1 x 6: ৳ 720.00)
Strip Price: ৳ 720.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftibuten dihydrate |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of mild-to-moderate infections caused by specific microorganisms
- Acute Bacterial Exacerbations of Chronic Bronchitis
- Acute Bacterial Otitis Media
- Pharyngitis and Tonsillitis
Pharmacology
Bactericidal action by binding to essential target proteins of the bacterial cell wall
Dosage & Administration
- Otitis Media:
- Adult Dosage: 400 mg orally every 24 hours for 10 days
- Pediatric Dosage: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days (>6 months)
- Tonsillitis/Pharyngitis:
- Adult Dosage: 400 mg orally every 24 hours for 10 days
- Pediatric Dosage: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days (>6 months)
- Bronchitis:
- Adult Dosage: 400 mg orally every 24 hours for 10 days
- Pediatric Dosage: 400 mg orally every 24 hours for 10 days (>12 years)
- Cystitis:
- Adult Dosage: 400 mg orally every 24 hours for 7 days
- Pediatric Dosage: 400 mg orally every 24 hours for 7 days (>12 years)
- Pneumonia:
- Adult Dosage: 200 mg orally every 12 hours for 7 to 14 days
- Pediatric Dosage: 200 mg orally every 12 hours for 7 to 14 days (>12 years)
- Sinusitis:
- Adult Dosage: 400 mg orally every 24 hours for 10 to 14 days
- Pediatric Dosage: 400 mg orally every 24 hours for 10 to 14 days (>12 years)
- Urinary tract Infection:
- Adult Dosage: 400 mg orally every 24 hours for 10 days
- Pediatric Dosage: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days (>6 months)
Interaction
- Theophylline & Antacid do not alter the pharmacokinetic profile of Zoventa
- Ranitidine increases the Cmax & AUC of Zoventa
Contraindications
Known allergy to the cephalosporin group of antibiotics
Side Effects
- Nausea
- Headache
- Diarrhea
- Dyspepsia
- Dizziness
- Abdominal pain
- Vomiting
Pregnancy & Lactation
Pregnancy Category B. Caution advised when administering to nursing women
Precautions & Warnings
- Resistant Organisms: Prolonged treatment may result in the possible emergence and overgrowth of resistant organisms
- Renal Insufficiency: Dose may require adjustment in patients with varying degrees of renal insufficiency
- Gastrointestinal Disease: Prescribed with caution to individuals with a history of gastrointestinal disease, particularly colitis
Use in Special Populations
- Renal Impairment:
- CrCl 5 to 29 ml/min: 2.25 mg/kg or 100 mg orally once a day
- CrCl 30 to 49 ml/min: 4.5 mg/kg or 200 mg orally once a day
- Hepatic Impairment: Dose adjustment is not necessary
Therapeutic Class
Third generation Cephalosporins
Reconstitution
- Contains purified water and granules
- Must be shaken well before use
Storage Conditions
Store below 25°C, protected from light and moisture. After reconstitution, the suspension may be used for 14 days while stored at 2°C to 8°C. Keep out of reach of children.