Buticef 400 mg (Capsule)
Unit Price: ৳ 120.00 (1 x 10: ৳ 1,200.00)
Strip Price: ৳ 1,200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftibuten dihydrate |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of acute bacterial exacerbations of chronic bronchitis
- Treatment of acute bacterial otitis media
- Treatment of pharyngitis and tonsillitis
Pharmacology
- Ceftibuten is the dihydrate salt of Ceftibuten
- Semi-synthetic Cephalosporin antibiotic
- Bactericidal action by binding to essential target proteins of the bacterial cell wall
Dosage & Administration
- Adult Dosage: 400 mg orally every 24 hours for 10 days
- Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
Interaction
- Theophylline & Antacid do not alter the pharmacokinetic profile of Buticef
- Ranitidine increases the Cmax & AUC of Buticef
Contraindications
- Contraindicated in patients with known allergy to the cephalosporin group of antibiotics
Side Effects
- Nausea
- Headache
- Diarrhea
- Dyspepsia
- Dizziness
- Abdominal pain
- Vomiting
Pregnancy & Lactation
- Pregnancy Category B
- Ceftibuten should be used in pregnancy only when the benefit clearly outweighs the risk
- Caution should be exercised when Ceftibuten is administered to nursing women
Precautions & Warnings
- Prolonged treatment may result in the possible emergence and overgrowth of resistant organisms
- Careful observation of the patient is essential
- Dose may require adjustment in patients with varying degrees of renal insufficiency
- Prescribed with caution to individuals with a history of gastrointestinal disease
Use in Special Populations
- Dose adjustment for patients with renal impairment
- No dose adjustment necessary for patients with hepatic impairment
Therapeutic Class
- Third generation Cephalosporins
Reconstitution
- Small bottle contains purified water and large bottle contains granules
- Prepared suspension to be consumed within 14 days of preparation if kept in a refrigerator
- Shake the bottle well each time before use
Storage Conditions
- Store below 25°C, protected from light and moisture
- After reconstitution, the suspension may be used for 14 days while stored at 2° to 8°C
- Keep out of reach of children