Buticef 400 mg (Capsule)

Unit Price: ৳ 120.00 (1 x 10: ৳ 1,200.00)
Strip Price: ৳ 1,200.00

Medicine Details

Indications

  • Treatment of acute bacterial exacerbations of chronic bronchitis
  • Treatment of acute bacterial otitis media
  • Treatment of pharyngitis and tonsillitis

Pharmacology

  • Ceftibuten is the dihydrate salt of Ceftibuten
  • Semi-synthetic Cephalosporin antibiotic
  • Bactericidal action by binding to essential target proteins of the bacterial cell wall

Dosage & Administration

  • Adult Dosage: 400 mg orally every 24 hours for 10 days
  • Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days

Interaction

  • Theophylline & Antacid do not alter the pharmacokinetic profile of Buticef
  • Ranitidine increases the Cmax & AUC of Buticef

Contraindications

  • Contraindicated in patients with known allergy to the cephalosporin group of antibiotics

Side Effects

  • Nausea
  • Headache
  • Diarrhea
  • Dyspepsia
  • Dizziness
  • Abdominal pain
  • Vomiting

Pregnancy & Lactation

  • Pregnancy Category B
  • Ceftibuten should be used in pregnancy only when the benefit clearly outweighs the risk
  • Caution should be exercised when Ceftibuten is administered to nursing women

Precautions & Warnings

  • Prolonged treatment may result in the possible emergence and overgrowth of resistant organisms
  • Careful observation of the patient is essential
  • Dose may require adjustment in patients with varying degrees of renal insufficiency
  • Prescribed with caution to individuals with a history of gastrointestinal disease

Use in Special Populations

  • Dose adjustment for patients with renal impairment
  • No dose adjustment necessary for patients with hepatic impairment

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Small bottle contains purified water and large bottle contains granules
  • Prepared suspension to be consumed within 14 days of preparation if kept in a refrigerator
  • Shake the bottle well each time before use

Storage Conditions

  • Store below 25°C, protected from light and moisture
  • After reconstitution, the suspension may be used for 14 days while stored at 2° to 8°C
  • Keep out of reach of children

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