Omiloc 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.00 (10 x 10: ৳ 500.00)

Strip Price: ৳ 50.00

Medicine Details

Category	Details
Generic	Omeprazole
Company	Kumudini pharma ltd

Gastric and duodenal ulcer
NSAID-associated duodenal and gastric ulcer
As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
Gastro-esophageal reflux disease
Long-term management of acid reflux disease
Acid-related dyspepsia
Severe ulcerating reflux esophagitis
Prophylaxis of acid aspiration during general anesthesia
Zollinger-Ellison syndrome
Helicobacter pylori-induced peptic ulcer

20 mg once daily for benign gastric and duodenal ulcer for 4 weeks in duodenal ulceration, 8 weeks in gastric ulceration
40 mg daily for severe or recurrent cases of benign gastric and duodenal ulcer
10-20 mg daily for long-term management of acid reflux disease
10-20 mg once daily for acid-related dyspepsia for 2-4 weeks
20 mg on the preceding evening, then 40 mg 2-6 hours before surgery for prophylaxis of acid aspiration
Initially 60 mg once daily for Zollinger-Ellison syndrome; usual range 20-120 mg daily
20 mg twice daily in association with antimicrobial agents for Helicobacter pylori eradication regimen in peptic ulcer disease

Omeprazole IV injection should be given as a slow intravenous injection
IV infusion over a period of 20-30 minutes or more
Use freshly prepared solution
Solution should be used within 4 hours of reconstitution for IV injection
Solution should be used within 12 hours when dissolved in saline and within 6 hours when dissolved in 5% Dextrose for IV infusion
Reconstituted solution should not be mixed or co-administered in the same infusion set with any other drug

Decreased intragastric acidity may reduce the absorption of ketoconazole
Metabolized in the liver through cytochrome P450
Can delay the elimination of diazepam, phenytoin, and warfarin
Monitoring of patients receiving warfarin or phenytoin is recommended
Plasma concentrations of Omeprazole and clarithromycin are increased during concomitant administration

Known hypersensitivity to Omeprazole
Suspected gastric ulcer, the possibility of malignancy should be excluded before treatment

Skin rash, urticaria, and pruritus
Photosensitivity, bullous eruption, erythema multiforme, angioedema, and alopecia
Diarrhoea, headache, constipation, nausea/vomiting, flatulence, and abdominal pain
Dry mouth, stomatitis, and candidiasis
Paraesthesia, dizziness, light headedness, and feeling faint
Somnolence, insomnia, and vertigo
Reversible mental confusion, agitation, depression, and hallucinations
Arthritic and myalgic symptoms
Blurred vision, taste disturbance, peripheral oedema, increased sweating, and gynaecomastia
Leucopenia, thrombocytopenia, agranulocytosis, pancytopenia, anaphylactic shock, malaise, and fever
Bronchospasm, encephalopathy in patients with pre-existing severe liver disease, hepatitis with or without jaundice, interstitial nephritis, and hepatic failure
Increases in liver enzymes

Results from three prospective epidemiological studies indicate no adverse effects on pregnancy or on the health of the fetus/newborn child
Omeprazole can be used during pregnancy
No information available on the passage of Omeprazole into breast milk or its effects on the neonate
Breastfeeding should be discontinued if the use of Omeprazole is considered essential

Avoid concomitant use of clopidogrel and Omeprazole
Observational studies suggest that PPI therapy may be associated with an increased risk for osteoporosis-related fractures
Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long-term with Omeprazole
Concomitant use of PPIs with methotrexate may lead to methotrexate toxicities