Roin 90 mg/5 ml (Powder for Suspension)
60 ml bottle: ৳ 480.00
Medicine Details
Category | Details |
---|---|
Generic | Ceftibuten dihydrate |
Company | Ziska pharmaceuticals ltd |
Also available as |
Indications
- Mild-to-moderte infections treatment
- Acute bacterial exacerbations of chronic bronchitis
- Acute bacterial otitis media treatment
- Pharyngitis and tonsillitis treatment
Pharmacology
- Ceftibuten as dihydrate salt
- Semi-synthetic Cephalosporin antibiotic
- Bactericidal action
- Inhibition of cell-wall synthesis
Dosage & Administration
- Adult dosage for Otitis Media: 400 mg orally every 24 hours for 10 days
- Pediatric dosage for Otitis Media: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
- Adult dosage for Tonsillitis/Pharyngitis: 400 mg orally every 24 hours for 10 days
- Pediatric dosage for Tonsillitis/Pharyngitis: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
- Adult dosage for Bronchitis: 400 mg orally every 24 hours for 10 days
- Pediatric dosage for Bronchitis: >12 years: 400 mg orally every 24 hours for 10 days
- Adult dosage for Cystitis: 400 mg orally every 24 hours for 7 days
- Pediatric dosage for Cystitis: >12 years: 400 mg orally every 24 hours for 7 days
- Adult dosage for Pneumonia: 200 mg orally every 12 hours for 7 to 14 days
- Pediatric dosage for Pneumonia: >12 years: 200 mg orally every 12 hours for 7 to 14 days
- Adult dosage for Sinusitis: 400 mg orally every 24 hours for 10 to 14 days
- Pediatric dosage for Sinusitis: >12 years: 400 mg orally every 24 hours for 10 to 14 days
- Adult dosage for Urinary tract Infection: 400 mg orally every 24 hours for 10 days
- Pediatric dosage for Urinary tract Infection: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
Interaction
- Theophylline & Antacid: No alteration to pharmacokinetics
- Ranitidine: Increases Cmax & AUC of Roin
Contraindications
- Known allergy to cephalosporin group of antibiotics
Side Effects
- Nausea
- Headache
- Diarrhea
- Dyspepsia
- Dizziness
- Abdominal pain
- Vomiting
Pregnancy & Lactation
- Pregnancy Category B
- No controlled data on use in pregnant women
- Caution in nursing women
Precautions & Warnings
- Possible emergence and overgrowth of resistant organisms
- Observation of the patient is essential
- Dose adjustment for patients with renal insufficiency
- Prescribed with caution to individuals with history of gastrointestinal disease
Use in Special Populations
- Renal Impairment: Dosage adjustment based on CrCl
- Hepatic Impairment: No dose adjustment necessary
Therapeutic Class
- Third generation Cephalosporins
Reconstitution
- Reconstitution process for suspension
- Prepared suspension to be consumed within 14 days of preparation if kept in a refrigerator
Storage Conditions
- Store below 25°C, protected from light and moisture
- Suspension: Usable for 14 days while stored at 2° to 8°C
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