Axeclav (125 mg+31.25 mg)/5 ml (Powder for Suspension)

70 ml bottle: ৳ 250.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Alco pharma ltd
Also available as
Axeclav 250 mg tablet Axeclav 500 mg tablet

Product Title

  • Axeclav 125 Suspension

Categories

  • Antibiotic
  • Medication
  • Infection Treatment

Description

  • Axeclav is indicated for the treatment of infections caused by sensitive bacteria

Dosage Form

  • Suspension

Dosage Strength

  • 125 mg

Dosage Frequency

  • Twice daily

Age Group

  • Adolescents
  • Adults
  • Paediatric Patients

Indicated Infections

  • Pharyngitis
  • Tonsillitis
  • Otitis Media
  • Sinusitis
  • Pneumonia
  • Bronchitis
  • Skin Infections
  • Urinary Tract Infections
  • Gonorrhoea
  • Lyme Disease
  • Septicemia
  • Meningitis
  • Typhoid Fever

Bactericidal Mechanism

  • Inhibits bacterial cell wall synthesis

Beta-lactamase Inhibitor

  • Clavulanic acid

Mechanism of Action

  • Interfering with the transpeptidation process
  • Inactivation of beta-lactamase enzymes

Duration of Treatment

  • 5-20 days depending on the infection type

Administration

  • With or without food

Storage Conditions

  • Store below 30°C, away from light and moisture

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort
  • Renal dysfunction
  • Anaphylaxis
  • Rash

Pregnancy Usage

  • Safe for later pregnancy stages
  • Excreted in breast milk in small quantities

Contraindications

  • Allergy to cephalosporin
  • Pseudomembranous Colitis

Drug Interactions

  • Probenecid
  • Gastric acidity reducing drugs

Precautions

  • Diuretic usage
  • History of colitis

Therapeutic Class

  • Second generation Cephalosporins

Bioavailability Enhancement

  • Combination with Clavulanic acid

Area Under Curve Increase

  • 50% with probenecid concomitant use

Usability Tip

  • Finish full course of treatment
  • Consult doctor before alcohol consumption

Infection Target Spectrum

  • Gram-positive
  • Gram-negative microbes

Antibiotic Resistance

  • Addresses resistance in beta-lactam capable bacteria

Infection Severity

  • From pharyngitis to septicemia

Treatment Flexibility

  • Switch therapy from injectable to oral

Treatment Response Time

  • Starts working within 2-3 hours

Duration of Effect

  • Lasts for 4-8 hours on average

Habit Forming

  • Non-habit forming tendencies reported

Postprandial Absorption

  • Effect of food intake on absorption

Efficacy Against

  • Beta-lactamase producing strains

Microorganism Overgrowth Risk

  • Possible with prolonged use

Stability

  • Sensitive to light and moisture

Child Safety

  • Keep out of reach of children

Patient Education

  • Importance of completing full treatment course

Max Daily Dosage

  • 1000 mg for Gonorrhoea

Dosage Adjustment

  • Based on age and infection type

Medication Safety

  • Avoid during first trimester if possible

Patient Monitoring

  • Watch for allergic reactions during use

Interaction Effect

  • Lower bioavailability with gastric acidity reducers

Symptoms of Side Effects

  • Abdominal cramps
  • Itchy rash
  • Breathing difficulties

Medication Disposal

  • Do not use leftover medicine for future infections

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