Omitac 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.00 (10 x 10: ৳ 500.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Omeprazole
Company Gaco pharmaceuticals ltd

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

Inhibitor of gastric acid secretion by blocking hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system in the gastric parietal cell

Dosage

  • Oral:
    • 20 mg once daily for 4-8 weeks in various conditions
    • 10-20 mg daily for long-term management of acid reflux disease
    • 40 mg on the preceding evening and 2-6 hours before surgery for prophylaxis of acid aspiration
    • Dose adjustments for Zollinger-Ellison syndrome and pediatric use
  • IV Injection:
    • Prophylaxis of acid aspiration
    • Duodenal ulcer, gastric ulcer, or reflux oesophagitis
    • Zollinger-Ellison syndrome

Administration

  • IV Injection: Given slowly over a period of 5 minutes as an intravenous injection
  • IV Infusion: Given as an intravenous infusion over a period of 20-30 minutes or more, dissolved in saline or 5% Dextrose

Interaction

  • Decreased intragastric acidity affecting the absorption of ketoconazole
  • Metabolism through cytochrome P450 affecting the elimination of certain drugs
  • Increased plasma concentrations during concomitant administration with other drugs

Contraindications

Known hypersensitivity

Side Effects

  • Mild and reversible adverse reactions
  • Skin rash, urticaria, pruritus, photosensitivity, bullous eruption
  • Diarrhoea, headache, constipation, nausea/vomiting
  • Dry mouth, stomatitis, candidiasis, paraesthesia
  • Dizziness, light headedness, somnolence, insomnia, vertigo
  • Reversible mental confusion, agitation, depression, hallucinations
  • Arthritic and myalgic symptoms, blurred vision, taste disturbance
  • Increased sweating, gynaecomastia, leucopenia, thrombocytopenia
  • Agranulocytosis, pancytopenia, anaphylactic shock, malaise, fever
  • Bronchospasm, encephalopathy, hepatitis with or without jaundice
  • Interstitial nephritis, hepatic failure, increases in liver enzymes observed

Pregnancy & Lactation

  • No adverse effects on pregnancy or on the health of the fetus/newborn child
  • Usage during pregnancy considered safe
  • No information available on the passage into breast milk or its effects on the neonate
  • Breastfeeding should be discontinued if essential
  • Safety and effectiveness not established in pediatric patients less than 18 years of age

Precautions & Warnings

  • Avoid concomitant use with clopidogrel
  • Increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted occasionally in long-term use
  • Concomitant use with methotrexate may lead to toxicities

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Keep in a dry place away from light and heat, out of the reach of children

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