Fixcef Plus 250 mg+62.5 mg (Tablet)

Unit Price: ৳ 34.50 (2 x 7: ৳ 483.00)
Strip Price: ৳ 241.50

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Navana pharmaceuticals ltd
Also available as
Fixcef plus 500 mg tablet

Title

  • Fixcef Plus 250 mg Tablet

Categories

  • Medicine
  • Antibiotic

Description

  • Treatment of infections caused by sensitive bacteria
  • Bactericidal second generation cephalosporin antibiotic
  • Active against a wide range of Gram-positive and Gram-negative susceptible organisms
  • Clavulanic acid acts as a beta-lactamase inhibitor
  • Dosage information for adolescents, adults, and pediatric patients
  • Contraindications and precautions for use
  • Storage conditions and therapeutic class

Color Options

  • NA

Functions

  • Bactericidal
  • Inhibits bacterial cell wall synthesis
  • Interferes with the transpeptidation process
  • Protects from degradation by beta lactamase enzymes
  • Provides a solution for the treatment of bacterial infections caused by beta lactam resistant bacteria

Materials

  • Cefuroxime
  • Clavulanic acid
  • Streptomyces clavuligerus

Dosage

  • 250 mg b.i.d. for adolescents and adults
  • 20 mg/kg/day b.i.d. for pediatric patients
  • Can be taken without regard of food

Interaction

  • Probenecid increases the area under the serum concentration versus time curve by 50% when administered with Cefuroxime-Clavulanic Acid
  • Drugs reducing gastric acidity may result in lower bioavailability

Contraindications

  • Known allergy to cephalosporin
  • Pseudomembranous Colitis

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Prolonged administration may result in overgrowth of nonsusceptible microorganisms
  • Rarely (<0.2%) renal dysfunction
  • Anaphylaxis
  • Angioedema
  • Pruritis
  • Rash
  • Serum sickness like urticaria

Pregnancy & Lactation

  • Avoid in first trimester if possible
  • Excreted into breast milk in small quantities

Precautions & Warnings

  • Given with care to patients receiving concurrent treatment with potent diuretics
  • History of colitis

Design Elements

  • NA

Usability Features

  • Starts working within 2-3 hours after taking
  • Effect lasts for an average duration of 4-8 hours
  • Safe to use in pregnancy and breastfeeding
  • Not habit forming
  • Quick tips for use provided

Dimensions

  • NA

Technical Specifications

  • N/A

Storage

  • Store in a cool, dry place below 30°C
  • Away from light and moisture
  • Keep out of the reach of children

Additional Features

  • Switch therapy (Injectable to oral)

Brand

  • Fixcef Plus

Manufacturer

  • NA

Model Number

  • 250 mg

Release Date

  • NA

Power Source

  • NA

Sustainable

  • NA

Warranty

  • NA

Care Instructions

  • NA

Age Range

  • NA

Safety Standards

  • NA

Certifications

  • NA

Assembled Product Dimensions (L x W x H)

  • NA

Indications

  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta-lactamase producing strains) or Streptococcus pyogenes
  • Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae (non beta-lactamase producing strains)
  • Lower respiratory tract infections including pneumonia caused by Streptococcus pneumoniae, Haemophilus influenzae (including beta lactamase-producing strains), Klebsiella spp., Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains), Streptococcus pyogenes, E. coli
  • Uncomplicated skin and skin-structure infections caused by Staphylococcus aureus (including beta-lactamase producing strains) or Streptococcus pyogenes
  • Uncomplicated urinary tract infections caused by E.coli or Klebsiella pneumoniae
  • Bone and Joint Infections caused by Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains)
  • Uncomplicated Gonorrhoea caused by penicillinase-producing and non-penicillinase producing strains of Neisseria gonorrhoeae
  • Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
  • Septicemia caused by Staphylococcus aureus, Streptococcus pneumoniae, E.coli, Haemophilus influenzae (including ampicillin-resistant strains) & Klebsiella spp.
  • Meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae (including ampicillin-resistant strains), Neisseria meningitidis &amp; Staphylococcus aureus (penicillinase and non-penicillinase producing strains)

Pharmacology

  • Cefuroxime is a bactericidal second generation cephalosporin antibiotic which is active against a wide range of Gram-positive and Gram-negative susceptible organisms including many beta-lactamase producing strains
  • Cefuroxime inhibits bacterial cell wall synthesis by interfering with the transpeptidation process
  • Clavulanic acid is a naturally derived beta lactamase inhibitor produced by Streptomyces clavuligerus
  • Clavulanic acid gives protection of Cefuroxime from degradation by beta lactamase enzymes and provides a solution for the treatment of bacterial infections caused by beta lactam resistant bacteria

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