Fixcef Plus 250 mg+62.5 mg (Tablet)
Unit Price: ৳ 34.50 (2 x 7: ৳ 483.00)
Strip Price: ৳ 241.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil clavulanic acid |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Title
- Fixcef Plus 250 mg Tablet
Categories
- Medicine
- Antibiotic
Description
- Treatment of infections caused by sensitive bacteria
- Bactericidal second generation cephalosporin antibiotic
- Active against a wide range of Gram-positive and Gram-negative susceptible organisms
- Clavulanic acid acts as a beta-lactamase inhibitor
- Dosage information for adolescents, adults, and pediatric patients
- Contraindications and precautions for use
- Storage conditions and therapeutic class
Color Options
- NA
Functions
- Bactericidal
- Inhibits bacterial cell wall synthesis
- Interferes with the transpeptidation process
- Protects from degradation by beta lactamase enzymes
- Provides a solution for the treatment of bacterial infections caused by beta lactam resistant bacteria
Materials
- Cefuroxime
- Clavulanic acid
- Streptomyces clavuligerus
Dosage
- 250 mg b.i.d. for adolescents and adults
- 20 mg/kg/day b.i.d. for pediatric patients
- Can be taken without regard of food
Interaction
- Probenecid increases the area under the serum concentration versus time curve by 50% when administered with Cefuroxime-Clavulanic Acid
- Drugs reducing gastric acidity may result in lower bioavailability
Contraindications
- Known allergy to cephalosporin
- Pseudomembranous Colitis
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal discomfort or pain
- Prolonged administration may result in overgrowth of nonsusceptible microorganisms
- Rarely (<0.2%) renal dysfunction
- Anaphylaxis
- Angioedema
- Pruritis
- Rash
- Serum sickness like urticaria
Pregnancy & Lactation
- Avoid in first trimester if possible
- Excreted into breast milk in small quantities
Precautions & Warnings
- Given with care to patients receiving concurrent treatment with potent diuretics
- History of colitis
Design Elements
- NA
Usability Features
- Starts working within 2-3 hours after taking
- Effect lasts for an average duration of 4-8 hours
- Safe to use in pregnancy and breastfeeding
- Not habit forming
- Quick tips for use provided
Dimensions
- NA
Technical Specifications
- N/A
Storage
- Store in a cool, dry place below 30°C
- Away from light and moisture
- Keep out of the reach of children
Additional Features
- Switch therapy (Injectable to oral)
Brand
- Fixcef Plus
Manufacturer
- NA
Model Number
- 250 mg
Release Date
- NA
Power Source
- NA
Sustainable
- NA
Warranty
- NA
Care Instructions
- NA
Age Range
- NA
Safety Standards
- NA
Certifications
- NA
Assembled Product Dimensions (L x W x H)
- NA
Indications
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta-lactamase producing strains) or Streptococcus pyogenes
- Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae (non beta-lactamase producing strains)
- Lower respiratory tract infections including pneumonia caused by Streptococcus pneumoniae, Haemophilus influenzae (including beta lactamase-producing strains), Klebsiella spp., Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains), Streptococcus pyogenes, E. coli
- Uncomplicated skin and skin-structure infections caused by Staphylococcus aureus (including beta-lactamase producing strains) or Streptococcus pyogenes
- Uncomplicated urinary tract infections caused by E.coli or Klebsiella pneumoniae
- Bone and Joint Infections caused by Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains)
- Uncomplicated Gonorrhoea caused by penicillinase-producing and non-penicillinase producing strains of Neisseria gonorrhoeae
- Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
- Septicemia caused by Staphylococcus aureus, Streptococcus pneumoniae, E.coli, Haemophilus influenzae (including ampicillin-resistant strains) & Klebsiella spp.
- Meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae (including ampicillin-resistant strains), Neisseria meningitidis & Staphylococcus aureus (penicillinase and non-penicillinase producing strains)
Pharmacology
- Cefuroxime is a bactericidal second generation cephalosporin antibiotic which is active against a wide range of Gram-positive and Gram-negative susceptible organisms including many beta-lactamase producing strains
- Cefuroxime inhibits bacterial cell wall synthesis by interfering with the transpeptidation process
- Clavulanic acid is a naturally derived beta lactamase inhibitor produced by Streptomyces clavuligerus
- Clavulanic acid gives protection of Cefuroxime from degradation by beta lactamase enzymes and provides a solution for the treatment of bacterial infections caused by beta lactam resistant bacteria