Rofuclav 250 mg+62.5 mg (Tablet)

Unit Price: ৳ 55.00 (2 x 7: ৳ 770.00)
Strip Price: ৳ 385.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Radiant pharmaceuticals ltd
Also available as
Rofuclav 500 mg tablet

Title

Rofuclav 250 mg Tablet

Categories

  • Pharmaceuticals
  • Medicine
  • Antibiotics

Description

Cefuroxime-Clavulanic Acid is indicated for the treatment of various bacterial infections. It inhibits bacterial cell wall synthesis and provides protection from degradation by beta-lactamase enzymes.

Color Options

  • White

Active Ingredients

  • Cefuroxime
  • Clavulanic acid

Dosage Form

Tablet

Dosage Strengths

  • Adolescents and Adults:
    • 250 mg
  • Paediatric Patients:
    • 20 mg/kg/day
    • 30 mg/kg/day

Dosage Administration

  • Pharyngitis/Tonsillitis: 250 mg b.i.d. for 5-10 days
  • Acute Bacterial Maxillary Sinusitis: 250 mg b.i.d. for 10 days
  • Acute Bacterial Exacerbation of Chronic Bronchitis: 250-500 mg b.i.d. for 10 days
  • Uncomplicated Urinary Tract Infections: 250 mg b.i.d. for 7-10 days
  • Uncomplicated Gonorrhoea: 1000 mg b.i.d. Single dose
  • Community Acquired Pneumonia: 250-500 mg b.i.d. for 5-10 days

Interaction

Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration versus time curve by 50%.

Contraindications

  • Known allergy to cephalosporin
  • Pseudomembranous Colitis

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Renal Dysfunction
  • Anaphylaxis
  • Angioedema
  • Pruritis
  • Rash

Pregnancy & Lactation

Avoid in first trimester, excreted into breast milk in small quantities

Precautions & Warnings

  • Given with care to patients receiving concurrent treatment with potent diuretics
  • History of colitis

Therapeutic Class

Second generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30°C), away from light and moisture

Usability Features

  • Well-tolerated
  • Can be taken without regard to food

Technical Specifications

  • Bactericidal second generation cephalosporin antibiotic
  • Active against wide range of Gram-positive and Gram-negative susceptible organisms
  • Inhibits bacterial cell wall synthesis
  • Derived beta lactamase inhibitor produced by Streptomyces clavuligerus
  • Similar structure to beta-lactam antibiotics
  • Irreversibly binds to beta-lactamase enzymes and inactivates them

Indications

  • Pharyngitis/Tonsillitis
  • Acute Bacterial Otitis Media
  • Acute Bacterial Maxillary Sinusitis
  • Lower respiratory tract infections
  • Uncomplicated skin and skin-structure infections
  • Uncomplicated urinary tract infections
  • Bone and Joint Infections
  • Uncomplicated Gonorrhoea
  • Early Lyme Disease
  • Septicemia
  • Meningitis
  • Switch therapy (Injectable to oral)

Commonly Asked Questions

  • What is Rofuclav 250 mg Tablet?
  • What is Rofuclav 250 mg Tablet used for?
  • How long does it take for Rofuclav 250 mg Tablet to take effect?
  • How long do the effects of this medicine last?
  • Is Rofuclav 250 mg Tablet safe to consume alcohol while taking this medicine?
  • Is Rofuclav 250 mg Tablet a habit forming medicine?
  • Can this medicine be taken during pregnancy?
  • Can Rofuclav 250 mg Tablet be taken while breast-feeding?

Quick Tips

  • Prescribed to treat bacterial infections
  • Finish the full course of treatment even if feeling better
  • Take with food to avoid upset stomach
  • Stop taking if itchy rash, swelling, or breathing difficulties occur

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