Rofuclav 500 mg+125 mg (Tablet)

Unit Price: ৳ 85.00 (2 x 7: ৳ 1,190.00)
Strip Price: ৳ 595.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Radiant pharmaceuticals ltd
Also available as
Rofuclav 250 mg tablet

Title

Rofuclav 500 mg Tablet

Categories

  • Antibiotic
  • Medication
  • Pharmaceutical

Description

Rofuclav 500 mg Tablet is a cephalosporin antibiotic combined with a beta-lactamase inhibitor, indicated for the treatment of various bacterial infections.

Indication

  • Pharyngitis/Tonsillitis
  • Acute Bacterial Otitis Media
  • Urinary Tract Infections
  • Skin and Skin-Structure Infections
  • Gonorrhoea
  • Lyme Disease
  • Meningitis
  • Switch Therapy

Pharmacology

Cefuroxime inhibits bacterial cell wall synthesis, while clavulanic acid protects cefuroxime from degradation by beta-lactamase enzymes.

Dosage and administration

  • Adolescents and adults:
      • Pharyngitis/Tonsillitis: 250 mg b.i.d. for 5-10 days
      • Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
      • Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
  • Paediatric patients:
      • Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
      • Acute otitis media: 30 mg/kg/day b.i.d for 10 days

Interaction

Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the serum concentration, while drugs that reduce gastric acidity may lower bioavailability.

Contraindications

Contraindicated in patients with known allergy to cephalosporin and in patients with Pseudomembranous Colitis.

Side effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Renal dysfunction
  • Anaphylaxis
  • Rash

Pregnancy and lactation

Avoid in first trimester. Can be used in later pregnancy and excreted into breast milk in small quantities.

Precautions and warnings

Use with care in patients receiving potent diuretics and with a history of colitis.

Therapeutic class

Second generation Cephalosporins

Storage conditions

Store below 30°C, away from light and moisture, keep out of the reach of children.

Common questions

  • What is Rofuclav 500 mg Tablet?: Cefuroxime is the cephalosporin antibiotic and Clavulanic acid is a beta-lactamase inhibitor, indicated for the treatment of infections caused by sensitive bacteria.
  • What is Rofuclav 500 mg Tablet used for?: To treat pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhoea, pneumonia, typhoid fever
  • How long does it take for Rofuclav 500 mg Tablet to take effect?: Starts working within 2-3 hours after taking it.
  • How long do the effects of this medicine last?: Lasts for an average duration of 4-8 hours.
  • Is Rofuclav 500 mg Tablet it safe to consume alcohol while taking this medicine?: Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is Rofuclav 500 mg Tablet a habit forming medicine?: No habit-forming tendencies reported.
  • Can this medicine be taken during pregnancy?: Safe to use in later pregnancy, recommended to consult a doctor.
  • Can Rofuclav 500 mg Tablet be taken while breast-feeding?: Safe to use during breastfeeding, excreted into breast milk at low levels.

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