Omrazol 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.50 (10 x 10: ৳ 550.00)
Strip Price: ৳ 55.00
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Ad din pharmaceuticals ltd |
Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
Inhibits gastric acid secretion by blocking hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
Dosage
- For benign gastric and duodenal ulcer: 20 mg once daily for 4 weeks in duodenal ulceration, 8 weeks in gastric ulceration
- For NSAID-associated duodenal or gastric ulcer: 20 mg once daily for 4 weeks, continued for further 4 weeks if not fully healed
- For gastro-esophageal reflux disease: 20 mg once daily for 4 weeks, continued for further 4-8 weeks if not fully healed
Administration
- Omeprazole IV injection should be given as a slow intravenous injection
- Omeprazole IV infusion should be given as an intravenous infusion
Interaction
- Decreases intragastric acidity, potentially reducing the absorption of ketoconazole during treatment
- Metabolized in the liver through cytochrome P450, potentially delaying the elimination of diazepam, phenytoin, and warfarin
Contraindications
Hypersensitivity to omeprazole, suspected gastric ulcer with possibility of malignancy
Side Effects
- Skin rash
- Diarrhea
- Headache
- Constipation
- Nausea/vomiting
Pregnancy & Lactation
Results from studies suggest no adverse effects on pregnancy or fetus/newborn child
Precautions & Warnings
Avoid concomitant use of clopidogrel, potential increased risk for osteoporosis-related fractures
Therapeutic Class
Proton Pump Inhibitor
Storage Conditions
Keep in a dry place away from light and heat, keep out of the reach of children
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