Omsec 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.00 (6 x 10: ৳ 300.00)
Strip Price: ৳ 50.00
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Techno drugs ltd |
Also available as |
Indications
- Treatment of gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer treatment
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease treatment
- Long-term management of acid reflux disease
- Acid-related dyspepsia treatment
- Severe ulcerating reflux esophagitis treatment
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome treatment
- Helicobacter pylori-induced peptic ulcer treatment
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of antisecretory effect within one hour
- Maximum effect within two hours
- Inhibition of secretion lasts up to 72 hours
- Gradual return of secretory activity over 3 to 5 days after discontinuation
Dosage
- 20 mg once daily for benign gastric and duodenal ulcer (4-8 weeks)
- 10-20 mg daily for long-term management of acid reflux disease
- 40 mg on the preceding evening, then 40 mg 2-6 hours before surgery for prophylaxis of acid aspiration
- Omeprazole regimen in different disease conditions
Administration
- Omeprazole IV injection for intravenous administration only
- Direction for use of IV Injection and IV Infusion
- Reconstitution guidelines for IV injection and infusion
- Use of freshly prepared solution
Interaction
- Decreased intragastric acidity affecting ketoconazole absorption
- Metabolism through cytochrome P450, potentially delaying elimination of certain drugs
- Monitoring and potential dose adjustment for patients receiving warfarin or phenytoin
- Plasma concentration changes during concomitant administration
- No evidence of interaction with certain drugs
Contraindications
- Known hypersensitivity to omeprazole
- Exclusion of malignancy before treatment in suspected gastric ulcer cases
Side Effects
- Mild and reversible adverse reactions
- Skin rash, urticaria, and pruritus
- Photosensitivity, bullous eruption, and erythema multiforme
- Diarrhoea, headache, constipation, nausea/vomiting, flatulence, and abdominal pain
- Dry mouth, stomatitis, and candidiasis
- Paraesthesia, dizziness, light headedness, and feeling faint
- Somnolence, insomnia, and vertigo
- Arthritic and myalgic symptoms
- Reversible mental confusion, agitation, depression, and hallucinations
- Increased liver enzymes
Pregnancy & Lactation
- No adverse effects on pregnancy or the health of the fetus/newborn child based on epidemiological studies
- Use during pregnancy, with breastfeeding discontinuation recommendation
- Safety and effectiveness not established in pediatric patients under 18 years of age
Precautions & Warnings
- Avoid concomitant use of clopidogrel and omeprazole
- Potential association of PPI therapy with increased risk for osteoporosis-related fractures
- Atrophic gastritis noted in long-term treated patients
- Potential methotrexate toxicities with PPIs
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
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