Omsec 40 mg/vial (IV Injection)
40 mg vial: ৳ 69.68
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Techno drugs ltd |
Also available as |
Indications
- Treatment of Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer treatment
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease treatment
- Long-term management of acid reflux disease
- Acid-related dyspepsia treatment
- Severe ulcerating reflux esophagitis treatment
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome treatment
- Helicobacter pylori-induced peptic ulcer treatment
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of the antisecretory effect within one hour
- Maximum effect occurring within two hours
- Inhibition of secretion lasting up to 72 hours
- Slow return of secretory activity over 3 to 5 days after discontinuation
Dosage
- Different dosages for specific conditions
- Oral and IV administration options
- Ranges from 10mg to 120mg depending on condition and patient weight
- Specific regimen for Helicobacter pylori eradication
- Different protocols for pediatric use
Administration
- IV Injection and IV Infusion directions
- Specific instructions for reconstitution and administration
- Use within specified time after reconstitution
- Precautions for co-administration with other drugs
Interaction
- Potential interactions with ketoconazole, diazepam, phenytoin, warfarin, clarithromycin, and antimicrobial agents
- No interaction with phenacetin, theophylline, caffeine, propranolol, metoprolol, cyclosporin, lidocaine, quinidine, estradiol, amoxycillin, antacids, piroxicam, diclofenac, naproxen, and digoxin
- Increased bioavailability of digoxin with simultaneous treatment
Contraindications
- Known hypersensitivity to omeprazole
- Exclusion of malignancy before treatment
Side Effects
- Mild and reversible adverse reactions
- Reports of skin rash, urticaria, pruritus, photosensitivity, bullous eruption, and alopecia
- Gastrointestinal reactions including diarrhea, headache, constipation, nausea/vomiting, flatulence, and abdominal pain
- Reports of dry mouth, stomatitis, candidiasis, paraesthesia, and dizziness
- Reversible mental confusion, agitation, depression, and hallucinations in severely ill patients
Pregnancy & Lactation
- No adverse effects on pregnancy or fetus/newborn child
- No information on passage into breast milk or effects on the neonate
- Discontinuation of breast-feeding if omeprazole use is essential
- Safety and effectiveness not established in pediatric patients
Precautions & Warnings
- Avoid concomitant use of clopidogrel and omeprazole
- Potential association of PPI therapy with increased risk for osteoporosis-related fractures
- Atrophic gastritis noted occasionally in long-term treated patients
- Potential for methotrexate toxicities with concomitant use of PPIs
Therapeutic Class
Proton Pump Inhibitor
Storage Conditions
Keep in a dry place away from light and heat
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