Cetriben 5 mg/5 ml (Syrup)

60 ml bottle: ৳ 30.00

Medicine Details

Indications

  • Relief of symptoms associated with seasonal & perennial allergic rhinitis
  • Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
  • Treatment of allergen-induced asthma

Pharmacology

  • Potent H1 receptor antagonist
  • No significant anticholinergic and antiserotonic effects
  • Inhibits histamine-mediated early phase of allergic reaction
  • Reduces migration of inflammatory cells and release of mediators
  • Peak plasma concentrations of 257 mcg/L within one hour of administration
  • Plasma half-life of approximately 11 hours

Dosage & Administration

  • Recommended dosage for adults and children 6 years and older: 1 tablet or 2 teaspoonfuls daily
  • Recommended dosage for children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoonful twice daily
  • Recommended dosage for children 6 months to 2 years: 1/2 teaspoonful once daily
  • Dosage form includes oral tablets and injectable form for intravenous administration

Interaction

  • No clinically significant drug interactions found with specific medications

Contraindications

  • Patients with a history of hypersensitivity to Cetirizine or hydroxyzine

Side Effects

  • Common side effect: somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category: B
  • Caution advised during pregnancy and lactation due to limited human studies

Precautions & Warnings

  • Caution advised when driving or operating heavy machinery

Use in Special Populations

  • Reduced clearance and increased AUC and half-life in hepatic or renal insufficiency
  • Safety demonstrated in pediatric patients aged 6 months to 5 years
  • Reduced clearance in elderly patients

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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