Opal 40 mg (Capsule (Enteric Coated))
Unit Price: ৳ 8.00 (8 x 4: ৳ 256.00)
Strip Price: ৳ 32.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
Inhibitor of gastric acid secretion
Dosage
- 20 mg once daily for 4 weeks in duodenal ulceration
- 8 weeks in gastric ulceration
- 40 mg daily for severe or recurrent cases
- 10-20 mg daily for acid-related dyspepsia
- 40 mg on the preceding evening for prophylaxis of acid aspiration
- 60 mg once daily for Zollinger-Ellison syndrome
- 20 mg twice daily with antimicrobial agents for Helicobacter pylori eradication regimen
Administration
Given as a slow intravenous injection or infusion
Interaction
- Decreased intragastric acidity affecting absorption of ketoconazole
- Metabolism through cytochrome P450 affecting elimination of diazepam, phenytoin, and warfarin
- Plasma concentrations increased during concomitant administration with clarithromycin
- Increased bioavailability of digoxin with simultaneous treatment
Contraindications
Known hypersensitivity to omeprazole
Side Effects
- Skin rash
- Diarrhea
- Headache
- Constipation
- Nausea/vomiting
- Dry mouth
- Dizziness
- Mental confusion
- Arthritic and myalgic symptoms
- Blurred vision
- Increased sweating
- Gynaecomastia
- Leucopenia
- Hepatitis
Pregnancy & Lactation
Safe for use during pregnancy; breastfeeding should be discontinued
Precautions & Warnings
- Avoid concomitant use with clopidogrel
- Increased risk for osteoporosis-related fractures
- Atrophic gastritis with long-term use
- Potential methotrexate toxicities with concomitant use
Therapeutic Class
Proton Pump Inhibitor
Storage Conditions
Keep in a dry place away from light and heat
Related Brands
- Opal 20 mg (Capsule (Enteric Coated)) - healthcare-pharmaceuticals-ltd
- OP-40 40 mg/vial (IV Injection) - globe-pharmaceuticals-ltd
- OP-40 40 mg (Capsule (Enteric Coated)) - globe-pharmaceuticals-ltd
- OP-20 20 mg (Capsule (Enteric Coated)) - globe-pharmaceuticals-ltd
- Seloktil 20 mg (Capsule (Enteric Coated)) - belsen-pharmaceuticals-ltd