Alermet 10 mg (Tablet)
Unit Price: ৳ 2.50 (100's pack: ৳ 250.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Orbit pharmaceuticals ltd |
| Also available as |
Indications
- Relief of symptoms associated with seasonal & perennial allergic rhinitis
- Treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria and allergen induced asthma
Pharmacology
- Potent H1 receptor antagonist
- No significant anticholinergic and antiserotonic effects
- Inhibition of histamine-mediated early phase of allergic reaction
- Reduction of migration of inflammatory cells and release of mediators associated with late phase of allergic reaction
- Peak plasma concentrations of 257 mcg/L within one hour of administration
- Plasma half-life of approximately 11 hours
- Renal clearance of 30 ml/minute
- Excretion half-life of approximately nine hours
Dosage & Administration
- Adult dosage: 1 tablet or 2 teaspoonfuls daily
- Children 2-6 years dosage: 1 teaspoonful once daily or 1/2 teaspoonful twice daily
- Children 6 months to 2 years dosage: 1/2 teaspoonful once daily
- Injectable dosage form for intravenous administration only
- Recommended dosage regimen for acute urticaria
- Dosage based on age and symptom severity
Interaction
- No clinically significant drug interactions found with specific medications
Contraindications
- Contraindicated in patients with hypersensitivity to Cetirizine or hydroxyzine
Side Effects
- Most common side effect is somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category B
- Cetirizine excreted in human milk
- Caution advised during pregnancy and lactation
Precautions & Warnings
- Caution advised when driving or operating heavy machinery
Use in Special Populations
- Effects in patients with hepatic or renal insufficiency
- Safety demonstrated in pediatric patients aged 6 months to 5 years
- Reduction in clearance in elderly patients
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children