Adtrizin 10 mg (Tablet)

Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00

Medicine Details

Indications

  • Relief of symptoms associated with seasonal allergic rhinitis
  • Relief of symptoms associated with perennial allergic rhinitis
  • Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
  • Treatment of allergen-induced asthma

Pharmacology

  • Potent H1 receptor antagonist
  • Histamine-mediated allergic reaction inhibition
  • Reduction of inflammatory cell migration
  • Reduction of mediator release in allergic reactions
  • Peak plasma concentration of 257 mcg/L within one hour (980 mcg/L in children)
  • Plasma half-life of approximately 11 hours
  • Consistent absorption from one subject to the next
  • Renal clearance of 30 ml/minute
  • Excretion half-life of approximately nine hours

Dosage & Administration

  • Adult dosage: 1 tablet or 2 teaspoonfuls daily
  • Children dosage: 1 teaspoonful once daily
  • Children 6 months to 2 years dosage: 1/2 teaspoonful once daily
  • Injectable dosage for adults: 10 mg administered by intravenous injection
  • Injectable dosage for children: 2.5 to 10 mg depending on age administered by intravenous injection

Interaction

  • No clinically significant drug interactions with Theophylline
  • No clinically significant drug interactions with Azithromycin
  • No clinically significant drug interactions with Pseudoephedrine
  • No clinically significant drug interactions with Ketoconazole
  • No clinically significant drug interactions with Erythromycin

Contraindications

  • Contraindicated in patients with hypersensitivity to Cetirizine or hydroxyzine

Side Effects

  • Most common side effect: somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category: B
  • Excreted in human milk
  • Caution advised when administered to nursing women

Precautions & Warnings

  • Caution advised when driving or operating heavy machinery

Use in Special Populations

  • Reduction of clearance in elderly patients
  • Safety demonstrated in pediatric patients aged 6 months to 5 years

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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