OPmax 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.00 (4 x 10: ৳ 320.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Omeprazole
Company Concord pharmaceuticals ltd
Also available as
Opmax 20 mg capsule

Title

  • OPmax

Categories

  • Medicine
  • Gastric Ulcer Treatment
  • Acid Reflux Medication
  • Proton Pump Inhibitor

Description

  • OPmax is a medicine used for the treatment of gastric and duodenal ulcers, NSAID-associated ulcers, gastro-esophageal reflux disease, acid-related dyspepsia, and other related conditions. It is also used for prophylaxis of acid aspiration during general anesthesia, Zollinger-Ellison syndrome, and Helicobacter pylori-induced peptic ulcers.

Dosage instructions

  • 20 mg once daily for 4-8 weeks for gastric and duodenal ulcer
  • 10-20 mg daily for long-term management of acid reflux disease
  • 40 mg on the preceding evening and 2-6 hours before surgery for prophylaxis of acid aspiration
  • 60-120 mg daily for Zollinger-Ellison syndrome
  • 20 mg twice daily with antimicrobial agents for Helicobacter pylori eradication regimen
  • 10-40 mg daily for severe ulcerating reflux esophagitis in pediatric use

Administration

  • IV injection should be given slowly over a period of 5 minutes as prophylaxis of acid aspiration
  • IV infusion should be given over a period of 20-30 minutes or more
  • Reconstituted solution should be used within 4-12 hours based on the diluent used

Pharmacology

  • Omeprazole is an inhibitor of gastric acid secretion that acts by blocking H+/K+ ATPase enzyme system in the gastric parietal cell.

Interaction

  • Decreased intragastric acidity may reduce the absorption of ketoconazole during OPmax treatment
  • OPmax can delay the elimination of diazepam, phenytoin, and warfarin due to its metabolism in the liver through cytochrome P450
  • Plasma concentrations of OPmax and clarithromycin are increased during concomitant administration

Contraindications

  • Known hypersensitivity to Omeprazole
  • Suspicion of gastric ulcer with possibility of malignancy

Side effects

  • Skin rash, urticaria, and pruritus
  • Photosensitivity, bullous eruption, and erythema multiforme
  • Diarrhea, headache, constipation, and nausea/vomiting
  • Dry mouth, stomatitis, and candidiasis

Pregnancy lactation

  • No adverse effects of Omeprazole on pregnancy or the health of the fetus/newborn child based on epidemiological studies
  • Discontinue breastfeeding if essential to use Omeprazole

Precautions warnings

  • Avoid concomitant use of clopidogrel and OPmax
  • PPI therapy may be associated with an increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted occasionally in long-term OPmax treatment
  • Concomitant use of PPIs with methotrexate may lead to toxicities

Therapeutic class

  • Proton Pump Inhibitor

Storage conditions

  • Keep in a dry place away from light and heat

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