Chlorphen 0.5% (Ophthalmic Solution)
10 ml drop: ৳ 30.00
Medicine Details
Category | Details |
---|---|
Generic | Chloramphenicol ophthalmic |
Company | Nipa pharmaceuticals ltd |
Also available as |
Indications
- Treatment of ocular infections involving the conjunctiva and/or cornea caused by Chlorphen-susceptible organisms
- Effective against Staphylococcus aureus, Streptococcus pneumoniae, E.coli, H. influenzae, Klebsiella/Enterobacter spp, Moraxella lacunata, and Neisseria species
Pharmacology
- Chloramphenicol is a broad-spectrum bacteriostatic antibiotic
- Inhibits bacterial protein synthesis by interfering with the transfer of activated amino acids from soluble RNA to ribosomes
Dosage & Administration
- Instill 1 or 2 drops in the conjunctival sac 4-6 times per day for the first 72 hours
- Subsequently, administer every 4 hours
- Treatment duration approximately 7 days
- Not to be continued for more than 3 weeks without re-evaluation by the physician
Interaction
Chymotrypsin may be inhibited if given simultaneously with Chlorphen
Contraindications
Contraindicated in individuals with a history of hypersensitivity to Chloramphenicol or any ingredients of the preparation
Side Effects
- Frequently reported adverse reactions such as burning, stinging, conjunctival hyperemia
- Other adverse reactions include blood dyscrasia, allergic or inflammatory reactions, vesicular and maculopapular dermatitis
Pregnancy & Lactation
Safety for use in pregnancy and lactation has not been established. Use only when considered essential by the physicians
Precautions & Warnings
- Not to be given for minor infections or for prophylaxis
- Repeated course and prolonged treatment should be avoided
- Blood dyscrasias may occur after prolonged ophthalmic use
Overdose Effects
Accidental ingestion unlikely to cause toxicity due to low antibiotic content
Therapeutic Class
- Ear Anti-Infectives & Antiseptics
- Eye Anti-Infectives & Antiseptics
- Macrolides
Storage Conditions
- Store in a cool (between 2°C-8°C) and dry place
- Protect from light
- Keep out of reach of children
- Do not touch the dropper tip to the surface
- Do not use after 30 days of the first opening
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