Chlorphen 0.5% (Ophthalmic Solution)

10 ml drop: ৳ 30.00

Medicine Details

Indications

  • Treatment of ocular infections involving the conjunctiva and/or cornea caused by Chlorphen-susceptible organisms
  • Effective against Staphylococcus aureus, Streptococcus pneumoniae, E.coli, H. influenzae, Klebsiella/Enterobacter spp, Moraxella lacunata, and Neisseria species

Pharmacology

  • Chloramphenicol is a broad-spectrum bacteriostatic antibiotic
  • Inhibits bacterial protein synthesis by interfering with the transfer of activated amino acids from soluble RNA to ribosomes

Dosage & Administration

  • Instill 1 or 2 drops in the conjunctival sac 4-6 times per day for the first 72 hours
  • Subsequently, administer every 4 hours
  • Treatment duration approximately 7 days
  • Not to be continued for more than 3 weeks without re-evaluation by the physician

Interaction

Chymotrypsin may be inhibited if given simultaneously with Chlorphen

Contraindications

Contraindicated in individuals with a history of hypersensitivity to Chloramphenicol or any ingredients of the preparation

Side Effects

  • Frequently reported adverse reactions such as burning, stinging, conjunctival hyperemia
  • Other adverse reactions include blood dyscrasia, allergic or inflammatory reactions, vesicular and maculopapular dermatitis

Pregnancy & Lactation

Safety for use in pregnancy and lactation has not been established. Use only when considered essential by the physicians

Precautions & Warnings

  • Not to be given for minor infections or for prophylaxis
  • Repeated course and prolonged treatment should be avoided
  • Blood dyscrasias may occur after prolonged ophthalmic use

Overdose Effects

Accidental ingestion unlikely to cause toxicity due to low antibiotic content

Therapeutic Class

  • Ear Anti-Infectives & Antiseptics
  • Eye Anti-Infectives & Antiseptics
  • Macrolides

Storage Conditions

  • Store in a cool (between 2°C-8°C) and dry place
  • Protect from light
  • Keep out of reach of children
  • Do not touch the dropper tip to the surface
  • Do not use after 30 days of the first opening

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