PPI 40 mg/vial (IV Injection)
40 mg vial: ৳ 90.00
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Acme laboratories ltd |
Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with history of NSAID-associated ulcers
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of antisecretory effect within one hour
- Maximum effect within two hours
- Inhibition of secretion lasts up to 72 hours
- Gradual return of secretory activity over 3 to 5 days upon discontinuation
Dosage
- Different dosage for different indications
- Oral and IV administration options
- Varied dosing based on patient's condition and age
- Recommendations for maintenance doses and prevention of relapse
Administration
- Directions for use of IV Injection and IV Infusion
- Recommendations for reconstitution and dilution
- Instructions on maximum rate of administration
- Limited shelf life after reconstitution
Interaction
- Impact on absorption of ketoconazole
- Metabolism through cytochrome P450 affecting diazepam, phenytoin, and warfarin
- Monitoring and potential dose adjustments for warfarin and phenytoin
- Data on concomitant treatment with various drugs
Contraindications
- Known hypersensitivity to omeprazole
- Exclusion of malignancy before treatment
Side Effects
- Mild and reversible adverse reactions
- Reports of skin rash, urticaria, and pruritus
- Cases of photosensitivity, bullous eruption, and alopecia
- Gastrointestinal reactions including diarrhea, headache, and more
Pregnancy & Lactation
- Results from prospective epidemiological studies
- Use of omeprazole during pregnancy
- Limited information on breastfeeding, with recommendation to discontinue if essential
Precautions & Warnings
- Avoid concomitant use of clopidogrel and PPI
- Potential association with increased risk for osteoporosis-related fractures
- Observations of atrophic gastritis in long-term use cases
- Caution with concomitant use of PPIs and methotrexate
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Instructions for storage in a dry place away from light and heat
- Advisory to keep out of the reach of children
Related Brands
- Prazo 20 mg (Capsule (Enteric Coated)) - pacific-pharmaceuticals-ltd
- Prazole 20 mg (Capsule (Enteric Coated)) - renata-limited
- Presec 20 mg (Capsule (Enteric Coated)) - unimed-unihealth-pharmaceuticals-ltd
- Prevas 20 mg (Capsule (Enteric Coated)) - general-pharmaceuticals-ltd
- Prevas 40 mg (Capsule (Enteric Coated)) - general-pharmaceuticals-ltd