Histal 4 mg (Tablet)

Unit Price: ৳ 0.21 (12 x 40: ৳ 100.80)
Strip Price: ৳ 8.40

Medicine Details

Category Details
Generic Chlorpheniramine maleate
Company Opsonin pharma ltd
Also available as

Indications

  • Urticaria
  • Sensitivity reactions
  • Angioneurotic edema
  • Vasomotor rhinitis
  • Cough
  • Common cold
  • Motion sickness
  • Other allergic conditions

Pharmacology

  • Chlorpheniramine Maleate is an alkylamine antihistamine
  • Potent histamine H1-receptor blocking agent
  • Less sedation than promethazine
  • Competitively blocks H1-receptor

Dosage & Administration

  • Adult dose: 4 mg every 4-6 hours, maximum 24 mg daily
  • Child doses: 6-12 years: 2 mg every 4-6 hours, maximum 12 mg daily
  • Child doses: 2-5 years: 1 mg every 4-6 hours, maximum 6 mg daily
  • Child doses: 1-2 years: 1 mg twice daily
  • Not recommended for use in infants below 1 year

Interaction

  • Incompatible with calcium chloride
  • Incompatible with kanamycin sulfate
  • Incompatible with noradrenaline acid tartrate
  • Incompatible with pentobarbital sodium
  • Incompatible with meglumine adipiodone

Contraindications

  • Hypersensitivity to chlorpheniramine
  • Contraindicated in newborn or premature infants

Side Effects

  • Well-tolerated
  • Possible drowsiness
  • Possible dizziness
  • Possible muscular weakness
  • Possible gastrointestinal upset

Pregnancy & Lactation

  • Not recommended for lactating mothers
  • Not recommended in pregnancy, especially during the first trimester

Precautions & Warnings

  • Use with caution in patients with glaucoma
  • Use with caution in patients with prostatic hypertrophy
  • Caution during driving and operating machinery

Overdose Effects

  • CNS depression (sedation, apnea, CV collapse)
  • CNS stimulation (insomnia, hallucination, tremors, convulsions)
  • Tinnitus
  • Blurred vision
  • Dizziness
  • Ataxia
  • Hypotension
  • More likely in children: Stimulation and atropine-like signs and symptoms (dry mouth, fixed dilated pupils, flushing, hyperthermia, GI symptoms)

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Store in a cool, dry place below 25°C
  • Protected from light
  • Keep out of the reach of children

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